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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Pro-neuregulin-1, membrane-bound isoform
Summary
- UniProt ID
- Q02297
- Gene Symbol
-
- NRG1
- GGF
- HGL
- HRGA
- NDF
- SMDF
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Chromosomal rearrangement
- Direct protein sequencing
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Growth factor
- Immunoglobulin domain
- Nucleus
- Reference proteome
- Secreted
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| glutamatergic synapse |
| apical plasma membrane |
| extracellular region |
| extracellular space |
| plasma membrane |
| membrane |
| nucleoplasm |
Sequence
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQEKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGRFSTQEEIQARLSSVIANQDPIAV
Glycosylation Sites
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Constitutive Signaling by Aberrant PI3K in Cancer | Homo sapiens |
| Downregulation of ERBB2 signaling | Homo sapiens |
| Downregulation of ERBB2:ERBB3 signaling | Homo sapiens |
| ERBB2 Activates PTK6 Signaling | Homo sapiens |
| ERBB2 Regulates Cell Motility | Homo sapiens |
| GRB2 events in ERBB2 signaling | Homo sapiens |
| GRB7 events in ERBB2 signaling | Homo sapiens |
| Long-term potentiation | Homo sapiens |
| Nuclear signaling by ERBB4 | Homo sapiens |
| PI3K events in ERBB2 signaling | Homo sapiens |
Human Protein Atlas