Downregulation of ERBB2:ERBB3 signaling

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
RNF41ERBB3:RNF41ERBB3-1UbUb-ERBB3Ub-RNF41ATPp-USP8USP8ADPUb-RNF41:p-USP8NRG1/2:p-10Y-ERBB3:p-ERBB2:RNF41Phosphorylated ERBB2:ERBB3 heterodimersNRG1/2:Ub-p-10Y-ERBB3:p-ERBB2
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025