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Retinal guanylyl cyclase 1

Summary

UniProt ID

Q02846

Gene Symbol

GUCY2D
CORD6
GUC1A4
GUC2D
RETGC
RETGC1

Organism

Homo sapiens (human)

External Links

GlyGen: Q02846
PubChem: Q02846
The Human Metabolome Database: HMDBP01067
The O-GlcNAc Database: Q02846

Annotation

Keyword

Cell projection
Cone-rod dystrophy
Congenital stationary night blindness
Disease variant
Disulfide bond
Endoplasmic reticulum
GTP-binding
Glycoprotein
Leber congenital amaurosis
Lyase
Reference proteome
Signal
Transmembrane helix
Vision
cGMP biosynthesis

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
regulation of rhodopsin mediated signaling pathway
cGMP biosynthetic process
receptor guanylyl cyclase signaling pathway
cGMP-mediated signaling
visual perception

Displaying **all 6** entries
GO Term
nuclear outer membrane
plasma membrane
photoreceptor outer segment
endoplasmic reticulum membrane
photoreceptor outer segment membrane
photoreceptor disc membrane

Displaying **all 9** entries
GO Term
protein homodimerization activity
adenylate cyclase activity
guanylate cyclase activity
ATP binding
GTP binding
peptide receptor activity
protein kinase activity
signaling receptor activity
protein-containing complex binding

Annotation information from UniProt.

Sequence

MTACARRAGGLPDPGLCGPAWWAPSLPRLPRALPRLPLLLLLLLLQPPALSAVFTVGVLGPWACDPIFSRARPDLAARLAAARLNRDPGLAGGPRFEVALLPEPCRTPGSLGAVSSALARVSGLVGPVNPAACRPAELLAEEAGIALVPWGCPWTQAEGTTAPAVTPAADALYALLRAFGWARVALVTAPQDLWVEAGRSLSTALRARGLPVASVTSMEPLDLSGAREALRKVRDGPRVTAVIMVMHSVLLGGEEQRYLLEAAEELGLTDGSLVFLPFDTIHYALSPGPEALAALANSSQLRRAHDAVLTLTRHCPSEGSVLDSLRRAQERRELPSDLNLQQVSPLFGTIYDAVFLLARGVAEARAAAGGRWVSGAAVARHIRDAQVPGFCGDLGGDEEPPFVLLDTDAAGDRLFATYMLDPARGSFLSAGTRMHFPRGGSAPGPDPSCWFDPNNICGGGLEPGLVFLGFLLVVGMGLAGAFLAHYVRHRLLHMQMVSGPNKIILTVDDITFLHPHGGTSRKVAQGSRSSLGARSMSDIRSGPSQHLDSPNIGVYEGDRVWLKKFPGDQHIAIRPATKTAFSKLQELRHENVALYLGLFLARGAEGPAALWEGNLAVVSEHCTRGSLQDLLAQREIKLDWMFKSSLLLDLIKGIRYLHHRGVAHGRLKSRNCIVDGRFVLKITDHGHGRLLEAQKVLPEPPRAEDQLWTAPELLRDPALERRGTLAGDVFSLAIIMQEVVCRSAPYAMLELTPEEVVQRVRSPPPLCRPLVSMDQAPVECILLMKQCWAEQPELRPSMDHTFDLFKNINKGRKTNIIDSMLRMLEQYSSNLEDLIRERTEELELEKQKTDRLLTQMLPPSVAEALKTGTPVEPEYFEQVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPQRNGQRHAAEIANMSLDILSAVGTFRMRHMPEVPVRIRIGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNLSTVGILRALDSGYQVELRGRTELKGKGAEDTFWLVGRRGFNKPIPKPPDLQPGSSNHGISLQEIPPERRRKLEKARPGQFS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites