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Cyclin-dependent kinase 5

Summary

UniProt ID

Q03114

Gene Symbol

Cdk5
Cdkn5
PSSALRE

Gene ID

140908

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: Q03114
PubChem: Q03114
O-GlcNAcAtlas: Q03114
Re-Glyco: Q03114

Annotation

Keyword

ATP-binding
Acetylation
Apoptosis
Biological rhythms
Cell division
Cell membrane
Cell projection
Cytoplasm
Neurodegeneration
Neurogenesis
Nucleus
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Synapse

Gene Ontology (GO)

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GO Term
nucleus
cytoplasm
plasma membrane
membrane
cell junction
axon
dendrite
neuromuscular junction
neuron projection
neuronal cell body

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
regulation of presynaptic cytosolic calcium ion concentration
regulation of synapse pruning
regulation of synaptic transmission, glutamatergic
regulation of postsynaptic membrane potential
excitatory postsynaptic potential
neuron migration
intracellular protein transport
exocytosis
apoptotic process
DNA damage response

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GO Term
kinase activity
cyclin-dependent protein serine/threonine kinase activity
ErbB-2 class receptor binding
ErbB-3 class receptor binding
histone H2AS1 kinase activity
p53 binding
protein kinase activity
protein serine/threonine kinase activity
ATP binding
cytoskeletal protein binding

Annotation information from UniProt.

Sequence

MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSLLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	GlyTouCan ID	Source
46	G49108TO	GlyGen
245	G49108TO	GlyGen
246	G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
CRMPs in Sema3A signaling	Rattus norvegicus
DARPP-32 events	Rattus norvegicus
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis	Rattus norvegicus
Regulation of TP53 Activity through Phosphorylation	Rattus norvegicus

Disease

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:12098	trigeminal neuralgia	Alliance of Genome Resources
DOID:1596	depressive disorder	Alliance of Genome Resources
DOID:2316	brain ischemia	Alliance of Genome Resources