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Sphingomyelin phosphodiesterase

Summary

UniProt ID

Q04519

Gene Symbol

Asm
Smpd1

Gene ID

20597

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003879
GlyGen: Q04519
PubChem: Q04519
Re-Glyco: Q04519

Annotation

Keyword

3D-structure
Disulfide bond
Glycoprotein
Glycosidase
Lipid droplet
Lipid metabolism
Lysosome
Metal-binding
Phosphoprotein
Reference proteome
Secreted
Signal
Zinc

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
plasma membrane
lipid droplet
endolysosome
lamellar body
extracellular space
lysosome

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 21 in total

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GO Term
response to tumor necrosis factor
response to cocaine
ceramide biosynthetic process
viral entry into host cell
cellular response to calcium ion
response to interleukin-1
response to ionizing radiation
response to type I interferon
cellular response to UV
negative regulation of MAPK cascade

Displaying **all 4** entries
GO Term
hydrolase activity, acting on glycosyl bonds
zinc ion binding
phosphatidylcholine phospholipase C activity
acid sphingomyelin phosphodiesterase activity

Annotation information from UniProt.

Sequence

MPHHRASSGQDHLRAGWEQRLERSLPAPRVGLLWMGLGLALVLALFDSTVLWVPARAYPLPSEGHSVKFSAIAPPLQSAFGWQNLTCPACKVLFTALNHGLKKEPNVARVGSVAIKICKMLNIAPLDVCQSAVHLFEDDVVEVWTRSVLSPSEACGLLLGSSCGHWDIFSTWNISLPSVPKPPPKPPSPPAPGAPVSRVLFLTDLHWDHEYLEGTDPYCADPLCCRRGSGWPPNSQKGAGFWGEYSKCDLPLRTLESLLKGLGPAGPFEMVYWTGDIPAHDVWQQSRQDQLRALTTITDLVRKFLGPVPVYPAVGNHESTPVNGFPPPFIKGNQSSQWLYEAMAKAWEPWLPADALHTLRIGGFYALTPRPGLRLISLNMNFCSRENFWLLINSTDPAGQLQWLVEELQAAENRGDKVHIIGHIPPGHCLKSWSWNYYKIIARYENTLAGQFFGHTHVDEFEIFYDEETLSRPLAVAFLAPSATTFINLNPGYRVYQIDGNYPGSSHVVLDHETYILNLTQANAAGGTPSWKRLYRARETYGLPDAMPASWHNLVYRMRDDEQLFQTFWFLYHKGHPPSEPCGTPCRLATLCAQLSARADSPALCRHLMPNGSLPDANRLWSRPLLC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
84	N-linked (GlcNAc...) asparagine	27435900	G10486CT	UniProt GlyGen
173	N-linked (GlcNAc...) asparagine	27435900		UniProt GlyGen
333	N-linked (GlcNAc...) asparagine	27435900	G80920RR	GlycoProtDB UniProt GlyGen
393	N-linked (GlcNAc...) asparagine	27435900		UniProt GlyGen
518	N-linked (GlcNAc...) asparagine	27435900		UniProt GlyGen
528				GlyGen
611	N-linked (GlcNAc...) asparagine		G80920RR	UniProt GlyGen