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Sphingomyelin phosphodiesterase

Summary

UniProt ID

Q04519

Gene Symbol

Smpd1
Asm

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003879
GlyGen: Q04519
PubChem: Q04519

Annotation

Keyword

3D-structure
Disulfide bond
Glycoprotein
Glycosidase
Lipid droplet
Lipid metabolism
Lysosome
Metal-binding
Phosphoprotein
Reference proteome
Secreted
Signal
Zinc

Gene Ontology (GO)

Displaying entries **11 - 20** of 21 in total

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GO Term
positive regulation of endocytosis
cellular response to calcium ion
termination of signal transduction
positive regulation of viral entry into host cell
cholesterol metabolic process
response to xenobiotic stimulus
cellular response to UV
plasma membrane repair
ceramide metabolic process
ceramide biosynthetic process

Displaying **all 6** entries
GO Term
extracellular space
lysosome
plasma membrane
lipid droplet
endolysosome
lamellar body

Displaying **all 4** entries
GO Term
acid sphingomyelin phosphodiesterase activity
hydrolase activity, acting on glycosyl bonds
zinc ion binding
phosphatidylcholine phospholipase C activity

Annotation information from UniProt.

Sequence

MPHHRASSGQDHLRAGWEQRLERSLPAPRVGLLWMGLGLALVLALFDSTVLWVPARAYPLPSEGHSVKFSAIAPPLQSAFGWQNLTCPACKVLFTALNHGLKKEPNVARVGSVAIKICKMLNIAPLDVCQSAVHLFEDDVVEVWTRSVLSPSEACGLLLGSSCGHWDIFSTWNISLPSVPKPPPKPPSPPAPGAPVSRVLFLTDLHWDHEYLEGTDPYCADPLCCRRGSGWPPNSQKGAGFWGEYSKCDLPLRTLESLLKGLGPAGPFEMVYWTGDIPAHDVWQQSRQDQLRALTTITDLVRKFLGPVPVYPAVGNHESTPVNGFPPPFIKGNQSSQWLYEAMAKAWEPWLPADALHTLRIGGFYALTPRPGLRLISLNMNFCSRENFWLLINSTDPAGQLQWLVEELQAAENRGDKVHIIGHIPPGHCLKSWSWNYYKIIARYENTLAGQFFGHTHVDEFEIFYDEETLSRPLAVAFLAPSATTFINLNPGYRVYQIDGNYPGSSHVVLDHETYILNLTQANAAGGTPSWKRLYRARETYGLPDAMPASWHNLVYRMRDDEQLFQTFWFLYHKGHPPSEPCGTPCRLATLCAQLSARADSPALCRHLMPNGSLPDANRLWSRPLLC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
84	N-linked (GlcNAc...) asparagine	27435900	G10486CT	UniProt GlyGen
173	N-linked (GlcNAc...) asparagine	27435900		UniProt GlyGen
333	N-linked (GlcNAc...) asparagine	27435900	G80920RR	GlycoProtDB UniProt GlyGen
393	N-linked (GlcNAc...) asparagine	27435900		UniProt GlyGen
518	N-linked (GlcNAc...) asparagine	27435900		UniProt GlyGen
611	N-linked (GlcNAc...) asparagine		G80920RR	UniProt GlyGen