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Platelet-derived growth factor receptor beta

Summary

UniProt ID

Q05030

Gene Symbol

Pdgfrb
Pdgfr
Pdgfr1

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: Q05030
The Human Metabolome Database: HMDBP12105

Annotation

Keyword

ATP-binding
Cell membrane
Chemotaxis
Cytoplasmic vesicle
Developmental protein
Disulfide bond
Glycoprotein
Immunoglobulin domain
Lysosome
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

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GO Term
positive regulation of cell migration
embryonic organ development
positive regulation of chemotaxis
response to organic cyclic compound
positive regulation of smooth muscle cell migration
adrenal gland development
response to estradiol
regulation of actin cytoskeleton organization
positive regulation of collagen biosynthetic process
response to lipid

Displaying **all 10** entries
GO Term
cytoplasmic vesicle
receptor complex
apical plasma membrane
ruffle
cell surface
lysosomal lumen
nucleus
cytoplasm
plasma membrane
membrane

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GO Term
enzyme binding
protein kinase binding
platelet-derived growth factor receptor activity
platelet-derived growth factor beta-receptor activity
platelet-derived growth factor receptor binding
ATP binding
vascular endothelial growth factor binding
platelet-derived growth factor binding
phosphatidylinositol 3-kinase binding
protein kinase activity

Annotation information from UniProt.

Sequence

MGLPEVMPASVLRGQLLLFVLLLLGPQISQGLVITPPGPEFVLNISSTFVLTCSSSAPVMWEQMSQVPWQEAAMNQDGTFSSVLTLTNVTGGDTGEYFCVYNNSLGPELSERKRIYIFVPDPTMGFLPMDSEDLFIFVTDVTETTIPCRVTDPQLEVTLHEKKVDIPLHVPYDHQRGFIGTFEDKTYICKTTIGDREVDSDTYYVYSLQVSSINVSVNAVQTVVRQGESITIRCIVMGNDVVNFQWTYPRMKSGRLVEPVTDYLFGVPSRIGSILHIPTAELSDSGTYTCNVSVSVNDHGDEKAINVTVIENGYVRLLETLEDVQIAELHRSRTLQVVFEAYPTPSVLWFKDNRTLGDSSAGELVLSTRNVSETRYVSELTLVRVKVSEAGYYTMRAFHADDQVQLSFKLQVNVPVRVLELSESHPANGEQILRCRGRGMPQPNVTWSTCRDLKRCPRKLSPTPLGNSSKEESQLETNVTFWEEDQEYEVVSTLRLRHVDQPLSVRCMLQNSMGRDSQEVTVVPHSLPFKVVVISAILALVVLTVISLIILIMLWQRKPRYEIRWKVIESVSSDGHEYIYVDPVQLPYDSTWELPRDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTFLQRHSNKHCPPSTELYSNALPVGLSLPSHLNLTGESDGGYMDMSKDESVDYVPMLDMKGHIKYADIESSSYMAPYDNYVPSAPERTYRATLINDSPVLSYTDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNDQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFETRPPFSQLVLLLERLLGEGYKKKYQQVDEEFLRSDHPAILRSQARLPGLHSLRSPLDTSSVLYTAVQPNETDNDYIIPLPDPKPDAADEGLLEGSPSLASSTLNEVNTSSTISCDSPLELQEEPQAEPEAQLEQPQDSGCPGPLAEAEDSFL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	Source
44	N-linked (GlcNAc...) asparagine	UniProt
88	N-linked (GlcNAc...) asparagine	UniProt
102	N-linked (GlcNAc...) asparagine	UniProt
214	N-linked (GlcNAc...) asparagine	UniProt
291	N-linked (GlcNAc...) asparagine	UniProt
306	N-linked (GlcNAc...) asparagine	UniProt
353	N-linked (GlcNAc...) asparagine	UniProt
370	N-linked (GlcNAc...) asparagine	UniProt
444	N-linked (GlcNAc...) asparagine	UniProt
467	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Downstream signal transduction	Rattus norvegicus
PI3K/AKT Signaling	Rattus norvegicus
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Rattus norvegicus
RAF/MAP kinase cascade	Rattus norvegicus
Signaling by PDGF	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements