Fibroblast growth factor receptor homolog 2

Summary
UniProt ID
Q09147
Gene Symbol
  • btl
  • FR2
  • HD-311
  • Tk2
Organism
Drosophila melanogaster (fruit fly)
PubChem
Q09147
Annotation
Keyword
  • ATP-binding
  • Developmental protein
  • Disulfide bond
  • Glycoprotein
  • Immunoglobulin domain
  • Phosphoprotein
  • Receptor
  • Reference proteome
  • Repeat
  • Signal
  • Transmembrane helix
  • Tyrosine-protein kinase
Gene Ontology (GO)
Sequence
MAKVPITLVMIIAIVSAAADLGCDYGHHRCYIDVTVENSPRQRHLLSDMDITLQCVRPMAKWFYEDKFQLRATLLRLERAQSGNSGNYGCLDSQNRWYNISLVVGHKEPVGNDIASFVKLEDAPALPESDLFFQPLNESRSLKLLQPLPKTVQRTAGGLFQLNCSPMDPDAKGVNISWLHNDTQILGGRGRIKLKRWSLTVGQLQPEDAGSYHCELCVEQDCQRSNPTQLEVISRKHTVPMLKPGYPRNTSIALGDNVSIECLLEDSALEPKITWLHKGNADNIDDLLQRLREQSQLPVDVTRLITRMDEPQVLRLGNVLMEDGGWYICIAENQVGRTVAASYVDLYSPSDTTTVRTTTTTTVASPIPTASTGEDNDDDVENPAAEASGGVGPPVFRKELKRLQHSLSGNTVNLACPVYGKANITWTKDKKPLNRELGVYVQKNWTLRFVEATSEDSGLYNCKVCNAWGCIQFDFSVQINDRTRSAPIIVVPQNQTVKVNGSLVMKCTVYSDLHPTVSWKRVVLKNASLDGLKSVEIQNLNFTVTNDSVVLTLRNVTFDQEGWYTCLASSGLGRSNSSVYLRVVSPLPPLEIYALLHAHPLGFTLAAITIVALFLLGSAFITFMLRRLRREKLLKLRIETVHQWTKKVIIYRPGGEEGSGCSSGDLQMPVIRIEKQRTTVSTTGTGGTDPAQGFNEYEFPLDSNWEIPRQQLSLGSILGEGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIADFGLARDIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTFAELVESFDGILQQASSNPNDAYLDLSMPMLETPPSSGDEDDGSDTETFRETSPLRYQYTYKFN
Glycosylation Sites
Displaying entries 1 - 10 of 15 in total
Position Description PubMed ID GlyTouCan ID Source
99 N-linked (GlcNAc...) asparagine
137 N-linked (GlcNAc...) asparagine
175 N-linked (GlcNAc...) asparagine
181 N-linked (GlcNAc...) asparagine
249 N-linked (GlcNAc...) asparagine
257 N-linked (GlcNAc...) asparagine
423 N-linked (GlcNAc...) asparagine
444 N-linked (GlcNAc...) asparagine
494 N-linked (GlcNAc...) asparagine
500 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying entries 1 - 10 of 34 in total
Pathway Name Organism
Downstream signaling of activated FGFR1 Drosophila melanogaster
FGFR1b ligand binding and activation Drosophila melanogaster
FGFR1c and Klotho ligand binding and activation Drosophila melanogaster
FGFR1c ligand binding and activation Drosophila melanogaster
FGFR2b ligand binding and activation Drosophila melanogaster
FGFR2c ligand binding and activation Drosophila melanogaster
FGFR3b ligand binding and activation Drosophila melanogaster
FGFR3c ligand binding and activation Drosophila melanogaster
FGFR4 ligand binding and activation Drosophila melanogaster
FRS-mediated FGFR1 signaling Drosophila melanogaster

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024