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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fibroblast growth factor receptor homolog 2
Summary
- UniProt ID
- Q09147
- Gene Symbol
-
- btl
- FR2
- HD-311
- Tk2
- Organism
- Drosophila melanogaster (fruit fly)
External Links
- PubChem
- Q09147
Annotation
- Keyword
-
- ATP-binding
- Developmental protein
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Gene Ontology (GO)
| GO Term |
|---|
| cytoneme |
| plasma membrane |
| receptor complex |
| GO Term |
|---|
| transmembrane receptor protein tyrosine kinase activity |
| fibroblast growth factor receptor activity |
| ATP binding |
Sequence
MAKVPITLVMIIAIVSAAADLGCDYGHHRCYIDVTVENSPRQRHLLSDMDITLQCVRPMAKWFYEDKFQLRATLLRLERAQSGNSGNYGCLDSQNRWYNISLVVGHKEPVGNDIASFVKLEDAPALPESDLFFQPLNESRSLKLLQPLPKTVQRTAGGLFQLNCSPMDPDAKGVNISWLHNDTQILGGRGRIKLKRWSLTVGQLQPEDAGSYHCELCVEQDCQRSNPTQLEVISRKHTVPMLKPGYPRNTSIALGDNVSIECLLEDSALEPKITWLHKGNADNIDDLLQRLREQSQLPVDVTRLITRMDEPQVLRLGNVLMEDGGWYICIAENQVGRTVAASYVDLYSPSDTTTVRTTTTTTVASPIPTASTGEDNDDDVENPAAEASGGVGPPVFRKELKRLQHSLSGNTVNLACPVYGKANITWTKDKKPLNRELGVYVQKNWTLRFVEATSEDSGLYNCKVCNAWGCIQFDFSVQINDRTRSAPIIVVPQNQTVKVNGSLVMKCTVYSDLHPTVSWKRVVLKNASLDGLKSVEIQNLNFTVTNDSVVLTLRNVTFDQEGWYTCLASSGLGRSNSSVYLRVVSPLPPLEIYALLHAHPLGFTLAAITIVALFLLGSAFITFMLRRLRREKLLKLRIETVHQWTKKVIIYRPGGEEGSGCSSGDLQMPVIRIEKQRTTVSTTGTGGTDPAQGFNEYEFPLDSNWEIPRQQLSLGSILGEGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIADFGLARDIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTFAELVESFDGILQQASSNPNDAYLDLSMPMLETPPSSGDEDDGSDTETFRETSPLRYQYTYKFN
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 99 | N-linked (GlcNAc...) asparagine |
|
||
| 137 | N-linked (GlcNAc...) asparagine |
|
||
| 175 | N-linked (GlcNAc...) asparagine |
|
||
| 181 | N-linked (GlcNAc...) asparagine |
|
||
| 249 | N-linked (GlcNAc...) asparagine |
|
||
| 257 | N-linked (GlcNAc...) asparagine |
|
||
| 423 | N-linked (GlcNAc...) asparagine |
|
||
| 444 | N-linked (GlcNAc...) asparagine |
|
||
| 494 | N-linked (GlcNAc...) asparagine |
|
||
| 500 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FRS-mediated FGFR2 signaling | Drosophila melanogaster |
| FRS-mediated FGFR3 signaling | Drosophila melanogaster |
| FRS-mediated FGFR4 signaling | Drosophila melanogaster |
| Negative regulation of FGFR1 signaling | Drosophila melanogaster |
| Negative regulation of FGFR2 signaling | Drosophila melanogaster |
| Negative regulation of FGFR3 signaling | Drosophila melanogaster |
| Negative regulation of FGFR4 signaling | Drosophila melanogaster |
| PI-3K cascade:FGFR1 | Drosophila melanogaster |
| PI-3K cascade:FGFR2 | Drosophila melanogaster |
| PI-3K cascade:FGFR3 | Drosophila melanogaster |
