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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Tumor suppressor candidate 3
Summary
- UniProt ID
- Q13454
- Gene Symbol
-
- TUSC3
- N33
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Disulfide bond
- Endoplasmic reticulum
- Intellectual disability
- Magnesium
- Reference proteome
- Signal
- Transmembrane helix
- Transport
- Gene Ontology (GO)
| GO Term |
|---|
| cognition |
| transmembrane transport |
| protein N-linked glycosylation via asparagine |
| protein N-linked glycosylation |
| magnesium ion transport |
| GO Term |
|---|
| plasma membrane |
| mitochondrion |
| endoplasmic reticulum membrane |
| oligosaccharyltransferase complex |
| GO Term |
|---|
| magnesium ion transmembrane transporter activity |
Sequence
MGARGAPSRRRQAGRRLRYLPTGSFPFLLLLLLLCIQLGGGQKKKENLLAEKVEQLMEWSSRRSIFRMNGDKFRKFIKAPPRNYSMIVMFTALQPQRQCSVCRQANEEYQILANSWRYSSAFCNKLFFSMVDYDEGTDVFQQLNMNSAPTFMHFPPKGRPKRADTFDLQRIGFAAEQLAKWIADRTDVHIRVFRPPNYSGTIALALLVSLVGGLLYLRRNNLEFIYNKTGWAMVSLCIVFAMTSGQMWNHIRGPPYAHKNPHNGQVSYIHGSSQAQFVAESHIILVLNAAITMGMVLLNEAATSKGDVGKRRIICLVGLGLVVFFFSFLLSIFRSKYHGYPYSDLDFE
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 83 |
|
|||
| 91 |
|
G62765YT
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Asparagine N-linked glycosylation | Homo sapiens |
| Maturation of spike protein | Homo sapiens |
| Miscellaneous transport and binding events | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1520 | colon carcinoma | |
| DOID:0050387 | nonpapillary renal cell carcinoma | |
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050865 | tongue squamous cell carcinoma | |
| DOID:0060308 | autosomal recessive intellectual developmental disorder | |
| DOID:0060810 | syndromic X-linked intellectual disability type 10 | |
| DOID:0060823 | syndromic X-linked intellectual disability 94 | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:0081183 | autosomal recessive intellectual developmental disorder 7 | |
| DOID:0110892 | inflammatory bowel disease 1 |
