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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Desmoglein-2
Summary
- UniProt ID
- Q14126
- Gene Symbol
-
- DSG2
- CDHF5
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011899
- GlyConnect
- GlyGen
- Q14126
- PubChem
- Q14126
- The Human Metabolome Database
- HMDBP07659
- The O-GlcNAc Database
- Q14126
- RaftProt
- Q14126
- O-GlcNAcAtlas
- Q14126
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cardiomyopathy
- Cell adhesion
- Cell junction
- Cell membrane
- Cleavage on pair of basic residues
- Disease variant
- Glycoprotein
- Metal-binding
- Palmitate
- Phosphoprotein
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| desmosome |
| GO Term |
|---|
| cell adhesion molecule binding |
| calcium ion binding |
| cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication |
Sequence
MARSPGRAYALLLLLICFNVGSGLHLQVLSTRNENKLLPKHPHLVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDREETPFFLLTGYALDARGNNVEKPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEPNTLNSKISYRIVSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEGMVEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAFHKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSESMDRSSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPVQTICHDAEYVNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQESTSVLLQQSEKKLGRSEIQFLISDNQGFSCPEKQVLTLTVCECLHGSGCREAQHDSYVGLGPAAIALMILAFLLLLLVPLLLLMCHCGKGAKGFTPIPGTIEMLHPWNNEGAPPEDKVVPSFLPVDQGGSLVGRNGVGGMAKEATMKGSSSASIVKGQHEMSEMDGRWEEHRSLLSGRATQFTGATGAIMTTETTKTARATGASRDMAGAQAAAVALNEEFLRNYFTDKAASYTEEDENHTAKDCLLVYSQEETESLNASIGCCSFIEGELDDRFLDDLGLKFKTLAEVCLGQKIDINKEIEQRQKPATETSMNTASHSLCEQTMVNSENTYSSGSSFPVPKSLQEANAEKVTQEIVTERSVSSRQAQKVATPLPDPMASRNVIATETSYVTGSTMPPTTVILGPSQPQSLIVTERVYAPASTLVDQPYANEGTVVVTERVIQPHGGGSNPLEGTQHLQDVPYVMVRERESFLAPSSGVQPTLAMPNIAVGQNVTVTERVLAPASTLQSSYQIPTENSMTARNTTVSGAGVPGPLPDFGLEESGHSNSTITTSSTRVTKHSTVQHSYS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 1055 |
|
|||
| 1056 |
|
|||
| 1059 |
|
|||
| 1060 |
|
|||
| 1065 |
|
|||
| 1073 |
|
|||
| 1097 |
|
|||
| 1108 |
|
G49108TO
G43669FQ
G59324HL
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Apoptotic cleavage of cell adhesion proteins | Homo sapiens |
| Formation of the cornified envelope | Homo sapiens |
| Keratinization | Homo sapiens |
| RAC2 GTPase cycle | Homo sapiens |
| RAC3 GTPase cycle | Homo sapiens |
| RHOG GTPase cycle | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
