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Transcription factor E2F2

Summary

UniProt ID

Q14209

Gene Symbol

E2F2

Organism

Homo sapiens (human)

External Links

GlyGen: Q14209
PubChem: Q14209
The O-GlcNAc Database: Q14209

Annotation

Keyword

3D-structure
Activator
Cell cycle
DNA-binding
Nucleus
Phosphoprotein
Reference proteome
Transcription regulation

Gene Ontology (GO)

Displaying **all 9** entries
GO Term
cell cycle
regulation of cell cycle
lens fiber cell apoptotic process
intrinsic apoptotic signaling pathway by p53 class mediator
regulation of DNA-templated transcription
regulation of transcription by RNA polymerase II
positive regulation of transcription by RNA polymerase II
transcription initiation at RNA polymerase II promoter
negative regulation of sprouting angiogenesis

Displaying **all 4** entries
GO Term
chromatin
nucleoplasm
RNA polymerase II transcription regulator complex
Rb-E2F complex

Displaying **all 9** entries
GO Term
protein dimerization activity
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA-binding transcription factor activity
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
cis-regulatory region sequence-specific DNA binding
DNA binding

Annotation information from UniProt.

Sequence

MLQGPRALASAAGQTPKVVPAMSPTELWPSGLSSPQLCPATATYYTPLYPQTAPPAAAPGTCLDATPHGPEGQVVRCLPAGRLPAKRKLDLEGIGRPVVPEFPTPKGKCIRVDGLPSPKTPKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQLIRKKAKNNIQWVGRGMFEDPTRPGKQQQLGQELKELMNTEQALDQLIQSCSLSFKHLTEDKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRTEDNLQIYLKSTQGPIEVYLCPEEVQEPDSPSEEPLPSTSTLCPSPDSAQPSSSTDPSIMEPTASSVPAPAPTPQQAPPPPSLVPLEATDSLLELPHPLLQQTEDQFLSPTLACSSPLISFSPSLDQDDYLWGLEAGEGISDLFDSYDLGDLLIN

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
104			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Cyclin D associated events in G1	Homo sapiens
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	Homo sapiens
Oncogene Induced Senescence	Homo sapiens
Oxidative Stress Induced Senescence	Homo sapiens