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Transcription factor E2F2

Summary

UniProt ID

Q14209

Gene Symbol

E2F2

Gene ID

1870

Organism

Homo sapiens (human)

External Links

GlyGen: Q14209
PubChem: Q14209
The O-GlcNAc Database: Q14209
Re-Glyco: Q14209

Annotation

Keyword

3D-structure
Activator
Cell cycle
DNA-binding
Nucleus
Phosphoprotein
Reference proteome
Transcription regulation

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
Rb-E2F complex
RNA polymerase II transcription regulator complex
chromatin
nucleoplasm

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 8** entries
GO Term
regulation of transcription by RNA polymerase II
transcription initiation at RNA polymerase II promoter
intrinsic apoptotic signaling pathway by p53 class mediator
negative regulation of sprouting angiogenesis
lens fiber cell apoptotic process
regulation of cell cycle
regulation of DNA-templated transcription
positive regulation of transcription by RNA polymerase II

Displaying **all 9** entries
GO Term
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA binding
DNA-binding transcription factor activity
sequence-specific DNA binding
protein dimerization activity
cis-regulatory region sequence-specific DNA binding
sequence-specific double-stranded DNA binding

Annotation information from UniProt.

Sequence

MLQGPRALASAAGQTPKVVPAMSPTELWPSGLSSPQLCPATATYYTPLYPQTAPPAAAPGTCLDATPHGPEGQVVRCLPAGRLPAKRKLDLEGIGRPVVPEFPTPKGKCIRVDGLPSPKTPKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQLIRKKAKNNIQWVGRGMFEDPTRPGKQQQLGQELKELMNTEQALDQLIQSCSLSFKHLTEDKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRTEDNLQIYLKSTQGPIEVYLCPEEVQEPDSPSEEPLPSTSTLCPSPDSAQPSSSTDPSIMEPTASSVPAPAPTPQQAPPPPSLVPLEATDSLLELPHPLLQQTEDQFLSPTLACSSPLISFSPSLDQDDYLWGLEAGEGISDLFDSYDLGDLLIN

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
104			G49108TO	The O-GlcNAc Database
355				GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Cyclin D associated events in G1	Homo sapiens
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	Homo sapiens
Oncogene Induced Senescence	Homo sapiens
Oxidative Stress Induced Senescence	Homo sapiens