GlyCosmos Portal

Submissions

[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial

Summary

UniProt ID

Q15118

Gene Symbol

PDHK1
PDK1

Gene ID

5163

Organism

Homo sapiens (human)

External Links

GlyGen: Q15118
PubChem: Q15118
The Human Metabolome Database: HMDBP01172
O-GlcNAcAtlas: Q15118
Re-Glyco: Q15118

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Kinase
Mitochondrion
Phosphoprotein
Reference proteome
Transit peptide

Gene Ontology (GO)

Displaying **all 3** entries
GO Term
mitochondrion
mitochondrial matrix
pyruvate dehydrogenase complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 7** entries
GO Term
glucose metabolic process
cell population proliferation
regulation of glucose metabolic process
phosphorylation
intrinsic apoptotic signaling pathway in response to oxidative stress
hypoxia-inducible factor-1alpha signaling pathway
regulation of acetyl-CoA biosynthetic process from pyruvate

Displaying **all 3** entries
GO Term
protein kinase activity
ATP binding
pyruvate dehydrogenase (acetyl-transferring) kinase activity

Annotation information from UniProt.

Sequence

MRLARLLRGAALAGPGPGLRAAGFSRSFSSDSGSSPASERGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKAIYDFTDTVIRIRNRHNDVIPTMAQGVIEYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGSPSHRKHIGSINPNCNVLEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRSA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites