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MIRAGE
Receptor tyrosine-protein kinase erbB-4
Summary
- UniProt ID
- Q15303
- Gene Symbol
-
- ERBB4
- HER4
- Gene ID
- 2066
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q15303
- PubChem
- Q15303
- The Human Metabolome Database
- HMDBP01376
- Re-Glyco
- Q15303
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Activator
- Alternative splicing
- Amyotrophic lateral sclerosis
- Apoptosis
- Cell membrane
- Developmental protein
- Disease variant
- Disulfide bond
- Glycoprotein
- Lactation
- Mitochondrion
- Nucleus
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transcription regulation
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| nucleus |
| mitochondrion |
| mitochondrial matrix |
| plasma membrane |
| neuromuscular junction |
| receptor complex |
| postsynaptic membrane |
| nucleoplasm |
| cytosol |
Sequence
MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 138 | N-linked (GlcNAc...) asparagine | |||
| 174 | N-linked (GlcNAc...) asparagine |
|
||
| 181 | N-linked (GlcNAc...) asparagine |
|
||
| 253 | N-linked (GlcNAc...) asparagine |
|
||
| 358 | N-linked (GlcNAc...) asparagine |
|
||
| 410 | N-linked (GlcNAc...) asparagine |
|
||
| 473 | N-linked (GlcNAc...) asparagine |
|
||
| 495 | N-linked (GlcNAc...) asparagine |
|
||
| 548 | N-linked (GlcNAc...) asparagine |
|
||
| 576 | N-linked (GlcNAc...) asparagine |
|
G31852PQ
G41247ZX
G02815KT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060210 | amyotrophic lateral sclerosis type 19 | |
| DOID:3748 | esophagus squamous cell carcinoma | |
| DOID:3910 | lung adenocarcinoma | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:9256 | colorectal cancer |
