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Receptor tyrosine-protein kinase erbB-4

Summary

UniProt ID

Q15303

Gene Symbol

ERBB4
HER4

Organism

Homo sapiens (human)

External Links

GlyGen: Q15303
PubChem: Q15303
The Human Metabolome Database: HMDBP01376

Annotation

Keyword

3D-structure
ATP-binding
Activator
Alternative splicing
Amyotrophic lateral sclerosis
Apoptosis
Cell membrane
Developmental protein
Disease variant
Disulfide bond
Glycoprotein
Lactation
Mitochondrion
Nucleus
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transcription regulation
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 38 in total

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GO Term
cardiac muscle tissue regeneration
establishment of planar polarity involved in nephron morphogenesis
positive regulation of protein localization to cell surface
protein autophosphorylation
neural crest cell migration
positive regulation of protein phosphorylation
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
nervous system development
synapse assembly

Displaying entries **11 - 16** of 16 in total

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GO Term
plasma membrane
neuromuscular junction
postsynaptic membrane
receptor complex
glutamatergic synapse
GABA-ergic synapse

Displaying **all 9** entries
GO Term
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
GABA receptor binding
protein homodimerization activity
transcription cis-regulatory region binding
epidermal growth factor receptor activity
epidermal growth factor receptor binding
ATP binding
neuregulin receptor activity

Annotation information from UniProt.

Sequence

MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 11 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
138	N-linked (GlcNAc...) asparagine	16203964	G31852PQ G41247ZX G02815KT	UniProt GlyGen
174	N-linked (GlcNAc...) asparagine	16203964		UniProt GlyGen
181	N-linked (GlcNAc...) asparagine			UniProt GlyGen
253	N-linked (GlcNAc...) asparagine	16203964		UniProt GlyGen
358	N-linked (GlcNAc...) asparagine	16203964		UniProt GlyGen
410	N-linked (GlcNAc...) asparagine	16203964		UniProt GlyGen
473	N-linked (GlcNAc...) asparagine	16203964		UniProt GlyGen
495	N-linked (GlcNAc...) asparagine	16203964		UniProt GlyGen
548	N-linked (GlcNAc...) asparagine			UniProt GlyGen
576	N-linked (GlcNAc...) asparagine	16203964		UniProt GlyGen