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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Ficolin-2
Summary
- UniProt ID
- Q15485
- Gene Symbol
-
- FCN2
- FCNL
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q15485
- The Human Metabolome Database
- HMDBP07683
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium
- Collagen
- Complement activation lectin pathway
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Hydroxylation
- Lectin
- Metal-binding
- Reference proteome
- Repeat
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| metal ion binding |
| carbohydrate derivative binding |
| proteoglycan binding |
| calcium-dependent protein binding |
| mannan binding |
| antigen binding |
| signaling receptor binding |
Sequence
MELDRAVGVLGAATLLLSFLGMAWALQAADTCPEVKMVGLEGSDKLTILRGCPGLPGAPGPKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGEPQPCLTGPRTCKDLLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRYLRGTHGSFANGINWKSGKGYNYSYKVSEMKVRPA
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Ficolins bind to repetitive carbohydrate structures on the target cell surface | Homo sapiens |
| Initial triggering of complement | Homo sapiens |
| Lectin pathway of complement activation | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:114 | heart disease | |
| DOID:11504 | autonomic neuropathy | |
| DOID:11514 | fissured tongue | |
| DOID:11714 | gestational diabetes | |
| DOID:11729 | Lyme disease | |
| DOID:11847 | coronary thrombosis | |
| DOID:11870 | Pick's disease | |
| DOID:11949 | Creutzfeldt-Jakob disease | |
| DOID:12140 | Chagas disease | |
| DOID:12177 | common variable immunodeficiency |
