Chagas disease

Summary
Synonym
  • Chagas' disease
  • chagas' disease with digestive system involvement
  • chagas' disease with nervous system involvement
  • chagas' disease with other organ involvement
Definition
A trypanosomiasis that is a tropical parasitic disease caused by the flagellate protozoan Trypanosoma cruzi, which is transmitted to humans and other mammals by an insect vector, the blood-sucking assassin bugs of the subfamily Triatominae (family Reduviidae), most commonly species belonging to the Triatoma, Rhodnius, and Panstrongylus genera. The symptoms include fever, fatigue, body aches, headache, rash, loss of appetite, diarrhea, vomiting, swelling of the eyelids and myocarditis.
Super Class
trypanosomiasis
Disease Ontology
DOID:12140
Mondo Disease Ontology
MeSH
UMLS
ORDO
GARD
Related Genes
Displaying all 10 entries
Gene ID Gene Symbol Description Source
1129 CHRM2 cholinergic receptor muscarinic 2
2147 F2 coagulation factor II, thrombin
3123 HLA-DRB1 major histocompatibility complex, class II, DR beta 1
3308 HSPA4 heat shock protein family A (Hsp70) member 4
3458 IFNG interferon gamma
5553 PRG2 proteoglycan 2, pro eosinophil major basic protein
6347 CCL2 C-C motif chemokine ligand 2
6352 CCL5 C-C motif chemokine ligand 5
6646 SOAT1 sterol O-acyltransferase 1
7431 VIM vimentin
Displaying all 7 entries
Gene ID Gene Symbol Description Source
14061 F2 coagulation factor II
14969 H2-Eb1 histocompatibility 2, class II antigen E beta
15978 Ifng interferon gamma
19074 Prg2 proteoglycan 2, bone marrow
20296 Ccl2 C-C motif chemokine ligand 2
22352 Vim vimentin
243764 Chrm2 cholinergic receptor, muscarinic 2, cardiac
Displaying all 5 entries
Gene ID Gene Symbol Description Source
24770 Ccl2 C-C motif chemokine ligand 2
25712 Ifng interferon gamma
58826 Prg2 proteoglycan 2, pro eosinophil major basic protein
81645 Chrm2 cholinergic receptor, muscarinic 2
81818 Vim vimentin
Displaying all 2 entries
Gene ID Gene Symbol Description Source
37892 mAChR-A muscarinic Acetylcholine Receptor, A-type
39557 Hsp110 Heat shock protein 110
Displaying 1 entry
Gene ID Gene Symbol Description Source
179962 gar-3 Muscarinic acetylcholine receptor gar-3

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024