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C3a anaphylatoxin chemotactic receptor
Summary
- UniProt ID
- Q16581
- Gene Symbol
-
- C3AR1
- AZ3B
- C3R1
- HNFAG09
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Chemotaxis
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Phosphoprotein
- Reference proteome
- Sulfation
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of cytosolic calcium ion concentration |
| positive regulation of vascular endothelial growth factor production |
| GO Term |
|---|
| plasma membrane |
| azurophil granule membrane |
| specific granule membrane |
| GO Term |
|---|
| G protein-coupled receptor activity |
| complement component C3a receptor activity |
| complement component C5a receptor activity |
Sequence
MASFSAETNSTDLLSQPWNEPPVILSMVILSLTFLLGLPGNGLVLWVAGLKMQRTVNTIWFLHLTLADLLCCLSLPFSLAHLALQGQWPYGRFLCKLIPSIIVLNMFASVFLLTAISLDRCLVVFKPIWCQNHRNVGMACSICGCIWVVAFVMCIPVFVYREIFTTDNHNRCGYKFGLSSSLDYPDFYGDPLENRSLENIVQPPGEMNDRLDPSSFQTNDHPWTVPTVFQPQTFQRPSADSLPRGSARLTSQNLYSNVFKPADVVSPKIPSGFPIEDHETSPLDNSDAFLSTHLKLFPSASSNSFYESELPQGFQDYYNLGQFTDDDQVPTPLVAITITRLVVGFLLPSVIMIACYSFIVFRMQRGRFAKSQSKTFRVAVVVVAVFLVCWTPYHIFGVLSLLTDPETPLGKTLMSWDHVCIALASANSCFNPFLYALLGKDFRKKARQSIQGILEAAFSEELTRSTHCPSNNVISERNSTTV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 9 | N-linked (GlcNAc...) asparagine |
|
||
| 194 | N-linked (GlcNAc...) asparagine |
|
||
| 233 |
|
|||
| 238 |
|
|||
| 266 | O-linked (GalNAc...) serine |
G43417UB
G29931IJ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| G alpha (i) signalling events | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
| Peptide ligand-binding receptors | Homo sapiens |
| Purinergic signaling in leishmaniasis infection | Homo sapiens |
| Regulation of Complement cascade | Homo sapiens |
