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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
High affinity nerve growth factor receptor
Summary
- UniProt ID
- Q3UFB7
- Gene Symbol
-
- Ntrk1
- Organism
- Mus musculus (house mouse)
External Links
- PubChem
- Q3UFB7
Annotation
- Keyword
-
- ATP-binding
- Cell membrane
- Developmental protein
- Differentiation
- Disulfide bond
- Endosome
- Glycoprotein
- Immunoglobulin domain
- Leucine-rich repeat
- Neurogenesis
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of GTPase activity |
| positive regulation of Ras protein signal transduction |
| neurotrophin TRK receptor signaling pathway |
| sympathetic nervous system development |
| response to axon injury |
| GO Term |
|---|
| early endosome |
| late endosome |
| cell surface |
| cytoplasm |
| plasma membrane |
| axon |
| dendrite |
| protein-containing complex |
| neuronal cell body |
| receptor complex |
| GO Term |
|---|
| neurotrophin binding |
Sequence
MLRGQRLGQLGWHRPAAGLGSLMTSLMLACASAASCREVCCPVGPSGLRCTRAGSLDTLRGLRGAGNLTELYVENQQHLQRLEFEDLQGLGELRSLTIVKSGLRFVAPDAFRFTPRLSHLNLSSNALESLSWKTVQGLSLQDLTLSGNPLHCSCALFWLQRWEQEGLCGVHTQTLHDSGPGDQFLPLGHNTSCGVPTVKIQMPNDSVEVGDDVFLQCQVEGLALQQADWILTELEGAATVKKFGDLPSLGLILVNVTSDLNKKNVTCWAENDVGRAEVSVQVSVSFPASVHLGLAVEQHHWCIPFSVDGQPAPSLRWLFNGSVLNETSFIFTQFLESALTNETMRHGCLRLNQPTHVNNGNYTLLAANPYGQAAASVMAAFMDNPFEFNPEDPIPVSFSPVDGNSTSRDPVEKKDETPFGVSVAVGLAVSAALFLSALLLVLNKCGQRSKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIMENPQYFSDTCVHHIKRQDIILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALKEASENARQDFQREAELLTMLQHQHIVRFFGVCTEGGPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFSTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREPQQRLSMKDVHARLQALAQAPPSYLDVLG
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 404 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ARMS-mediated activation | Mus musculus |
| Frs2-mediated activation | Mus musculus |
| PI3K/AKT activation | Mus musculus |
| Retrograde neurotrophin signalling | Mus musculus |
| TRKA activation by NGF | Mus musculus |
