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Metabotropic glutamate receptor 5

Summary

UniProt ID

Q3UVX5

Gene Symbol

Grm5
Gprc1e
Mglur5

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0004966

GlyConnect

2510

GlyGen

Q3UVX5

PubChem

Q3UVX5

O-GlcNAcAtlas

Q3UVX5

Annotation

Keyword

Alternative splicing
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Methylation
Phosphoprotein
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 19 in total

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GO Term
modulation of chemical synaptic transmission
regulation of synaptic transmission, glutamatergic
G protein-coupled glutamate receptor signaling pathway
regulation of protein phosphorylation
learning
positive regulation of MAPK cascade
synapse organization
positive regulation of calcium-mediated signaling
cellular response to amyloid-beta
desensitization of G protein-coupled receptor signaling pathway

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GO Term
dendrite
neuron projection
postsynaptic membrane
dendritic spine
dendritic shaft
Schaffer collateral - CA1 synapse
postsynaptic density membrane
glutamatergic synapse
astrocyte projection
cytoplasm

Displaying **all 10** entries
GO Term
G protein-coupled receptor activity
G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential
PLC activating G protein-coupled glutamate receptor activity
protein tyrosine kinase activator activity
glutamate receptor activity
identical protein binding
protein tyrosine kinase binding
adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
A2A adenosine receptor binding
neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration

Annotation information from UniProt.

Sequence

MVLLLILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLLKKLRSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNLRNPWFQEFWQHRFQCRLEGFAQENSKYNKTCNSSLTLRTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGLCDAMKPIDGRKLLDSLMKTNFTGVSGDMILFDENGDSPGRYEIMNFKEMGKDYFDYINVGSWDNGELKMDDDEVWSKKNNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVIFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTSTVVRMHVGDGKSSSAASRSSSLVNLWKRRGSSGETLRYKDRRLAQHKSEIECFTPKGSMGNGGRATMSSSNGKSVTWAQNEKSTRGQHLWQRLSVHINKKENPNQTAVIKPFPKSTESRGQGAGAGGGSGPGAAGAGSAGCTATGGPEPPDAGPKALYDVAEAEERFPAAARPRSPSPISTLSHLAGSAGRTDDDAPSLHSETAARSSSSQGSLMEQISSVVTRFTANITELNSMMLSTAAAPGPPGTPICSSYLIPKEIQLPTTMTTFAEIQPLPAIEVTGGAQPATGPSPAQETPAGAEAAPGKPDLEELVALTPPSPFRDSVDSGSTTPNSPVSESALCIPSSPKYDTLIIRDYTQSSSSL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	GlyTouCan ID	Source
88	N-linked (GlcNAc...) asparagine	G90575OW	UniProt GlyGen
209	N-linked (GlcNAc...) asparagine	G02815KT	UniProt GlyGen
377	N-linked (GlcNAc...) asparagine	G10819WX G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
381	N-linked (GlcNAc...) asparagine	G39446WN	GlycoProtDB UniProt GlyGen
444	N-linked (GlcNAc...) asparagine	G60967DT	UniProt GlyGen
733	N-linked (GlcNAc...) asparagine		UniProt GlyGen
943		G62765YT	GlyGen
1042		G49108TO	GlyGen
1046		G49108TO	GlyGen
1049		G49108TO	GlyGen