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Metabotropic glutamate receptor 5

Summary

UniProt ID

Q3UVX5

Gene Symbol

Grm5
Gprc1e
Mglur5

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0004966

GlyConnect

2510

GlyGen

Q3UVX5

PubChem

Q3UVX5

O-GlcNAcAtlas

Q3UVX5

Annotation

Keyword

Alternative splicing
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Methylation
Phosphoprotein
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 19 in total

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GO Term
modulation of chemical synaptic transmission
regulation of synaptic transmission, glutamatergic
G protein-coupled glutamate receptor signaling pathway
regulation of protein phosphorylation
learning
positive regulation of MAPK cascade
synapse organization
positive regulation of calcium-mediated signaling
cellular response to amyloid-beta
desensitization of G protein-coupled receptor signaling pathway

Displaying entries **1 - 10** of 11 in total

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GO Term
dendrite
neuron projection
postsynaptic membrane
dendritic spine
dendritic shaft
Schaffer collateral - CA1 synapse
postsynaptic density membrane
glutamatergic synapse
astrocyte projection
cytoplasm

Displaying **all 10** entries
GO Term
G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential
PLC activating G protein-coupled glutamate receptor activity
protein tyrosine kinase activator activity
glutamate receptor activity
identical protein binding
protein tyrosine kinase binding
adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
A2A adenosine receptor binding
neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
G protein-coupled receptor activity

Annotation information from UniProt.

Sequence

MVLLLILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLLKKLRSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNLRNPWFQEFWQHRFQCRLEGFAQENSKYNKTCNSSLTLRTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGLCDAMKPIDGRKLLDSLMKTNFTGVSGDMILFDENGDSPGRYEIMNFKEMGKDYFDYINVGSWDNGELKMDDDEVWSKKNNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVIFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTSTVVRMHVGDGKSSSAASRSSSLVNLWKRRGSSGETLRYKDRRLAQHKSEIECFTPKGSMGNGGRATMSSSNGKSVTWAQNEKSTRGQHLWQRLSVHINKKENPNQTAVIKPFPKSTESRGQGAGAGGGSGPGAAGAGSAGCTATGGPEPPDAGPKALYDVAEAEERFPAAARPRSPSPISTLSHLAGSAGRTDDDAPSLHSETAARSSSSQGSLMEQISSVVTRFTANITELNSMMLSTAAAPGPPGTPICSSYLIPKEIQLPTTMTTFAEIQPLPAIEVTGGAQPATGPSPAQETPAGAEAAPGKPDLEELVALTPPSPFRDSVDSGSTTPNSPVSESALCIPSSPKYDTLIIRDYTQSSSSL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites