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MIRAGE
RAC-beta serine/threonine-protein kinase
Summary
- UniProt ID
- Q60823
- Gene Symbol
-
- Akt2
- Gene ID
- 11652
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Acetylation
- Apoptosis
- Cell membrane
- Cytoplasm
- Developmental protein
- Disulfide bond
- Endosome
- Glucose metabolism
- Glycogen biosynthesis
- Glycogen metabolism
- Glycoprotein
- Manganese
- Metal-binding
- Nucleus
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Sugar transport
- Translation regulation
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| plasma membrane |
| cell cortex |
| nucleoplasm |
| early endosome |
| cytosol |
| ruffle membrane |
Sequence
MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRGPGEDAMDYKCGSPSDSSTSEMMEVAVNKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLDPLELDQRTHFPQFSYSASIRE
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | Mus musculus |
| FLT3 Signaling | Mus musculus |
| G beta:gamma signalling through PI3Kgamma | Mus musculus |
| Inhibition of TSC complex formation by PKB | Mus musculus |
| KEAP1-NFE2L2 pathway | Mus musculus |
| Negative regulation of the PI3K/AKT network | Mus musculus |
| PI3K/AKT Signaling | Mus musculus |
| RAB GEFs exchange GTP for GDP on RABs | Mus musculus |
| Regulation of PTEN stability and activity | Mus musculus |
| Regulation of TP53 Activity through Acetylation | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11612 | polycystic ovary syndrome | |
| DOID:9352 | type 2 diabetes mellitus |
