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Rho guanine nucleotide exchange factor 2

Summary

UniProt ID

Q60875

Gene Symbol

Arhgef2
Kiaa0651
Lbcl1
Lfc

Gene ID

16800

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q60875
RaftProt: Q60875
Re-Glyco: Q60875

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Coiled coil
Cytoplasmic vesicle
Cytoskeleton
Developmental protein
Differentiation
Golgi apparatus
Guanine-nucleotide releasing factor
Innate immunity
Microtubule
Mitosis
Neurogenesis
Phosphoprotein
Proto-oncogene
Reference proteome
Tight junction
Zinc-finger

Gene Ontology (GO)

Displaying entries **1 - 10** of 14 in total

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GO Term
cytoplasm
cytoskeleton
cytoplasmic vesicle
vesicle
protein-containing complex
neuronal cell body
Golgi apparatus
podosome
spindle
microtubule

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 17 in total

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GO Term
innate immune response
negative regulation of neurogenesis
actin filament organization
positive regulation of transcription by RNA polymerase II
asymmetric neuroblast division
cellular response to muramyl dipeptide
establishment of mitotic spindle orientation
cell morphogenesis
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production

Displaying **all 4** entries
GO Term
guanyl-nucleotide exchange factor activity
microtubule binding
small GTPase binding
metal ion binding

Annotation information from UniProt.

Sequence

MSRIESLTRARIDRSKEQATKTREKEKMKEAKDARYTNGHLFTTISVSGMTMCYACNKSITAKEALICPTCNVTIHNRCKDTLANCTKVKQKQQKAALLRNNTALQSVSLRSKTTTRERPTSAIYPSDSFRQSLLGSRRGLSSLSLAKSVSTTNIAGHFNDESPLGLRQILSQSTDSLNMRNRTLSVESLIDEGVEVFYNELMSDFEMDEKDFEADSWSLAVDSSFLQQHKKEVMKKQDVIYELIQTELHHVRTLKIMTRLFRTGMLEELQMEPEVVQGLFPCVDELSDIHTRFLNQLLERRRQALCPGSTRNFVIHRLGDLLISQFSGSNAEQMRKTYSEFCSRHTKALKLYKELYARDKRFQQFIRKMTRSAVLKRHGVQECILLVTQRITKYPVLINRILQNSHGVEEEYQDLASALGLVKELLSNVDQDVHELEKEARLQEIYNRMDPRAQTPVPGKGPFGRDELLRRKLIHEGCLLWKTATGRFKDVLLLLMTDVLVFLQEKDQKYIFTSLDKPSVVSLQNLIVRDIANQAKGMFLISSGPPEMYEVHAASRDDRTTWIRVIQQSVRLCPSREDFPLIETEDKAYLRRIKTKLQQKNQALVELLQKNVELFAEMVHFQALKAGFVGMPPPALPRGLFRLESFESLRGERLLKDALREVEGLKDLLLGPCVDLPMTSREPALPLDSDSGSCPGVTANGEARTFNGSIELCRADSDSSQKDRNGNQLRSPQEEVLQPLINLYGLLHGLQAVVVQQERLMEALFPEGPERWEKLSRANSRDGEAGRAAVASVTPEKQATELALLQRQHTLLQEELRRCQRLGEERATEAGSLEARLRESEQARALLEREAEEIRRQLAALGQNEPLPAEAPWARRPLDPRRRSLPAGDALYLSFNPPQPSRGHDRLDLPVTVRSLHRPFDDREAQELGSPEDRLQDSSDPDTGSEEEVSSRLSPPHSPRDFTRMQDIPEETESRDGEPTASES

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites