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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Rho guanine nucleotide exchange factor 1
Summary
- UniProt ID
- Q61210
- Gene Symbol
-
- Arhgef1
- Lbcl2
- Lsc
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Coiled coil
- Cytoplasm
- GTPase activation
- Guanine-nucleotide releasing factor
- Membrane
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| microtubule depolymerization |
| G protein-coupled receptor signaling pathway |
| GO Term |
|---|
| cytosol |
| cytoplasm |
| plasma membrane |
| GO Term |
|---|
| G protein-coupled receptor binding |
| guanyl-nucleotide exchange factor activity |
| GTPase activator activity |
Sequence
MGEVAGGAAPGPPRSGLVSIIIGAEDEDFENELEANSEDQNSQFQSLEQVKRRPAHLMALLQHVALQFEPGPLLCCLHADMLSSLGPKEAKKAFLDFYHSFLEKTAVLRVPVPPSVAFELDRTRPDLISEDVQRRFIQEVVQSQQAAVSRQLEDFRSKRLMGMTPWEQELSLLEPWIGKDRGNYEARERHVAERLLSHLEETQHTISTDEEKSAAVVTAISLYMRHLGVRTKSGDKKSGRNFFRKKVMGNRRSDEPPKTKKGLSSILDPARWNRGEPSAPDCRHLKVEADAEKPGPADRKGGLGMSSRDRTVGTPGQDNPGVSLHPLSTDSVDSREPGVDTPQEPGDTPPQGPTSLEPLAPPESTEDNGETESPEPGDDGEPGRSGLELEPEEPPGWRELVPPDTLLSLPKSQVKRQEVISELLVTEAAHVRMLRVLHDLFYQPMADGGFFPLDELQNIFPSLDELIEVHSLFLDRLMKRRQESGYLIEEIGDVLLARFDGAEGSWFQKISSRFCSRQSFALEQLKAKQRKEPRFCAFVQEAESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQNTEESTERGKVELAAECCREILHHVNQAVRDMEDLLRLKDYQRRLDLTHLRQSSDPMLSEFKNLDITKKKLVHEGPLTWRVTKDKAIEVHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTMLRPVLRLTSAMTREVATDHKAFYVIFTWDQEAQIYELVAQTSSERKNWCNLITETAGSLKVPAPASRLKPRPSPSSIREPLLSSSENGTGGAEMAPADARTERLLNDLLPFCRPGPEGQLAATALQKVLSLKQILLSTEEDSGAGPPRDGDGVPGGRAPGPVHTQEIEENLLSLEVAIRQLEELEEEFCRLRPLLSQLGGTLSPNLAAPERSAQTGLS
Glycosylation Sites
G09700PF
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| G alpha (12/13) signalling events | Mus musculus |
| NRAGE signals death through JNK | Mus musculus |
| RHOA GTPase cycle | Mus musculus |
| RHOB GTPase cycle | Mus musculus |
| RHOC GTPase cycle | Mus musculus |
