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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Receptor tyrosine-protein kinase erbB-4
Summary
- UniProt ID
- Q61527
- Gene Symbol
-
- Erbb4
- Mer4
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0005494
- GlyConnect
- GlyGen
- Q61527
- PubChem
- Q61527
Annotation
- Keyword
-
- ATP-binding
- Activator
- Alternative splicing
- Apoptosis
- Cell membrane
- Developmental protein
- Disulfide bond
- Glycoprotein
- Lactation
- Mitochondrion
- Nucleus
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transcription regulation
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| plasma membrane |
| neuromuscular junction |
| postsynaptic membrane |
| basal plasma membrane |
| presynaptic membrane |
| postsynaptic density membrane |
| dendrite |
| neuronal cell body |
| receptor complex |
Sequence
MKLATGLWVWGSLLMAAGTVQPSASQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNMTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIDAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRRAENCTAEGMVCNHLCSNDGCWGPGPDQCLSCRRFSRGKICIESCNLYDGEFREFENGSICVECDSQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADQDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGGLFILVIMALTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRTRIDSNRSEIGHSPPPAYTPMSGNQFVYQDGGFATQQGMPMPYRATTSTIPEAPVAQGATAEMFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERNPRGELDEEGYMTPMHDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHSASSGPPKAEDEYVNEPLYLNTFANALGSAEYMKNSVLSVPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTMLPPPPYRHRNTVV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 138 | N-linked (GlcNAc...) asparagine | |||
| 174 | N-linked (GlcNAc...) asparagine | |||
| 181 | N-linked (GlcNAc...) asparagine |
|
||
| 253 | N-linked (GlcNAc...) asparagine |
|
||
| 358 |
|
|||
| 410 | N-linked (GlcNAc...) asparagine |
|
||
| 473 | N-linked (GlcNAc...) asparagine |
|
||
| 495 | N-linked (GlcNAc...) asparagine |
|
||
| 548 | N-linked (GlcNAc...) asparagine | |||
| 576 | N-linked (GlcNAc...) asparagine |
G41247ZX
G95177YH
G02815KT
G06110VR
G80920RR
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Downregulation of ERBB2 signaling | Mus musculus |
| Downregulation of ERBB4 signaling | Mus musculus |
| ERBB2 Activates PTK6 Signaling | Mus musculus |
| ERBB2 Regulates Cell Motility | Mus musculus |
| Estrogen-dependent gene expression | Mus musculus |
| GRB2 events in ERBB2 signaling | Mus musculus |
| Nuclear signaling by ERBB4 | Mus musculus |
| PI3K events in ERBB2 signaling | Mus musculus |
| PI3K events in ERBB4 signaling | Mus musculus |
| PI3K/AKT Signaling | Mus musculus |
