PI3K events in ERBB2 signaling

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Phosphorylated ERBB2:ERBB3 heterodimersNRG1/2:p-ERBB3:p-ERBB2:PI3KPIK3CA:PIK3R1PIP2ADPATPPIP3Phosphorylated ERBB2:ERBB4cyt1 heterodimersNRGs/EGFLs:p-ERBB4cyt1:p-ERBB2:PI3KGRB2:GAB1EGF:p-EGFR:p-ERBB2:GRB2:GAB1Phosphorylated ERBB2:EGFR heterodimersEGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025