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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Heat shock 70 kDa protein 1A
Summary
- UniProt ID
- Q61696
- Gene Symbol
-
- Hspa1a
- Hsp70-3
- Hsp70A1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Acetylation
- Chaperone
- Cytoskeleton
- Direct protein sequencing
- Methylation
- Nucleus
- Phosphoprotein
- Reference proteome
- Secreted
- Stress response
- Gene Ontology (GO)
| GO Term |
|---|
| negative regulation of transcription by RNA polymerase II |
| telomere maintenance |
| mRNA catabolic process |
| response to unfolded protein |
| response to heat |
| GO Term |
|---|
| nuclear speck |
Sequence
MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPGAGGFGAQAPKGASGSGPTIEEVD
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 636 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| AUF1 (hnRNP D0) binds and destabilizes mRNA | Mus musculus |
| Attenuation phase | Mus musculus |
| HSF1-dependent transactivation | Mus musculus |
| HSP90 chaperone cycle for SHRs | Mus musculus |
| Mitochondrial unfolded protein response (UPRmt) | Mus musculus |
| Neutrophil degranulation | Mus musculus |
| PKR-mediated signaling | Mus musculus |
| Regulation of HSF1-mediated heat shock response | Mus musculus |
