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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fibroblast growth factor receptor 3
Summary
- UniProt ID
- Q61851
- Gene Symbol
-
- Fgfr3
- Mfr3
- Sam3
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Alternative splicing
- Apoptosis
- Cell membrane
- Cytoplasmic vesicle
- Disulfide bond
- Endoplasmic reticulum
- Glycoprotein
- Immunoglobulin domain
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| lysosome |
| plasma membrane |
| cytoplasmic vesicle |
| receptor complex |
| endoplasmic reticulum |
| cytoplasmic side of plasma membrane |
| cell surface |
| perinuclear region of cytoplasm |
| GO Term |
|---|
| protein tyrosine kinase activity |
| fibroblast growth factor receptor activity |
| fibroblast growth factor binding |
| ATP binding |
| miRNA binding |
Sequence
MVVPACVLVFCVAVVAGATSEPPGPEQRVVRRAAEVPGPEPSQQEQVAFGSGDTVELSCHPPGGAPTGPTVWAKDGTGLVASHRILVGPQRLQVLNASHEDAGVYSCQHRLTRRVLCHFSVRVTDAPSSGDDEDGEDVAEDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAILGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELMETDEAGSVYAGVLSYGVVFFLFILVVAAVILCRLRSPPKKGLGSPTVHKVSRFPLKRQVSLESNSSMNSNTPLVRIARLSSGEGPVLANVSELELPADPKWELSRTRLTLGKPLGEGCFGQVVMAEAIGIDKDRTAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGMDYSFDACRLPEEQLTCKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTPGGPSPYPGIPVEELFKLLKEGHRMDKPASCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRILTVTSTDEYLDLSVPFEQYSPGGQDTPSSSSSGDDSVFTHDLLPPGPPSNGGPRT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 96 | N-linked (GlcNAc...) asparagine | |||
| 219 | N-linked (GlcNAc...) asparagine | |||
| 256 | N-linked (GlcNAc...) asparagine | |||
| 288 | N-linked (GlcNAc...) asparagine |
|
||
| 309 | N-linked (GlcNAc...) asparagine |
|
||
| 322 | N-linked (GlcNAc...) asparagine |
|
||
| 424 |
|
G20528HD
G62765YT
G64527OM
G05724UK
G14972EH
G80920RR
G04657PL
G50282JC
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FGFR3b ligand binding and activation | Mus musculus |
| FGFR3c ligand binding and activation | Mus musculus |
| FRS-mediated FGFR3 signaling | Mus musculus |
| Negative regulation of FGFR3 signaling | Mus musculus |
| PI-3K cascade:FGFR3 | Mus musculus |
| PI3K Cascade | Mus musculus |
| PI3K/AKT Signaling | Mus musculus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Mus musculus |
| Phospholipase C-mediated cascade; FGFR3 | Mus musculus |
| RAF/MAP kinase cascade | Mus musculus |
