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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Nucleophosmin
Summary
- UniProt ID
- Q61937
- Gene Symbol
-
- Npm1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- ADP-ribosylation
- Acetylation
- Chaperone
- Cytoskeleton
- DNA-binding
- Direct protein sequencing
- Disulfide bond
- Isopeptide bond
- Nucleus
- Phosphoprotein
- RNA-binding
- Reference proteome
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| regulation of centrosome duplication |
| positive regulation of centrosome duplication |
| positive regulation of cell cycle G2/M phase transition |
| negative regulation of mRNA splicing, via spliceosome |
| cellular senescence |
| GO Term |
|---|
| nucleus |
| nucleolus |
| cytoplasm |
| granular component |
| nucleoplasm |
| centrosome |
| large ribosomal subunit |
| small ribosomal subunit |
| ribonucleoprotein complex |
| nuclear matrix |
| GO Term |
|---|
| unfolded protein binding |
| p53 binding |
| rRNA binding |
| ATP binding |
| phosphatidylinositol-3,4,5-trisphosphate binding |
| histone binding |
Sequence
MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEDEEDVKLLGMSGKRSAPGGGNKVPQKKVKLDEDDEDDDEDDEDDEDDDDDDFDEEETEEKVPVKKSVRDTPAKNAQKSNQNGKDLKPSTPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKVEAKFINYVKNCFRMTDQEAIQDLWQWRKSL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 75 |
|
|||
| 82 |
|
|||
| 88 |
|
|||
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Deposition of new CENPA-containing nucleosomes at the centromere | Mus musculus |
| PKR-mediated signaling | Mus musculus |
| SUMOylation of transcription cofactors | Mus musculus |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | Mus musculus |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | Mus musculus |
