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1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

Summary

UniProt ID

Q62077

Gene Symbol

Plcg1
Plcg-1

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q62077
PubChem: Q62077

Annotation

Keyword

Acetylation
Calcium
Cell projection
Hydrolase
Lipid degradation
Metal-binding
Phosphoprotein
Reference proteome
Repeat
SH2 domain
SH3 domain
Transducer
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 22 in total

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GO Term
modulation of chemical synaptic transmission
positive regulation of vascular endothelial cell proliferation
positive regulation of endothelial cell apoptotic process
phosphatidylinositol catabolic process
T cell receptor signaling pathway
release of sequestered calcium ion into cytosol
positive regulation of release of sequestered calcium ion into cytosol
phosphatidylinositol metabolic process
epidermal growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling

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GO Term
glutamatergic synapse
lamellipodium
clathrin-coated vesicle
cytosol
ruffle
COP9 signalosome
ruffle membrane
cytoplasm
plasma membrane
cell-cell junction

Displaying **all 10** entries
GO Term
calcium-dependent phospholipase C activity
phosphoprotein binding
phosphatidylinositol phospholipase C activity
phospholipase C activity
guanyl-nucleotide exchange factor activity
insulin receptor binding
neurotrophin TRKA receptor binding
receptor tyrosine kinase binding
glutamate receptor binding
calcium ion binding

Annotation information from UniProt.

Sequence

MAGVATPCANGCGPGAPSEAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGSIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAATPLQIERWLRKQFYSVDRNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLETNALRTGERPEHCQVSLSEFQQFLLEYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDELVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQHFRKVLGDTLLTKPVDIAADGLPSPNQLRRKILIKHKKLAEGSAYEEVPTSVMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEASSSTELHSSEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQDGGWWRGDYGGKKQLWFPSNYVEEMINPAVLEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSISMPSVAQWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCVICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAKENGDLSPFSGISLRERASDASSQLFHVRAREGSFEARYQQPFEDFRISQEHLADHFDSRERSTSDGPSSATNLIEDPLHDKLWKCSL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **11 - 19** of 19 in total

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Pathway Name	Organism
Phospholipase C-mediated cascade: FGFR1	Mus musculus
Phospholipase C-mediated cascade; FGFR2	Mus musculus
Phospholipase C-mediated cascade; FGFR3	Mus musculus
Phospholipase C-mediated cascade; FGFR4	Mus musculus
RET signaling	Mus musculus
Role of phospholipids in phagocytosis	Mus musculus
Signaling by ALK	Mus musculus
Synthesis of IP3 and IP4 in the cytosol	Mus musculus
VEGFR2 mediated cell proliferation	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Summary

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Annotation

International Collaboration

Acknowledgements