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Glycan Structure Repository
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Glycomics MS raw data Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Repository for lectin-assisted multimodality data
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Guidelines
MIRAGE
Leptin receptor
Summary
- UniProt ID
- Q62959
- Gene Symbol
-
- Fa
- Lepr
- Obr
- Gene ID
- 24536
- Organism
- Rattus norvegicus (Norway rat)
External Links
- Re-Glyco
- Q62959
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Disease variant
- Disulfide bond
- Glycoprotein
- Obesity
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular space |
| receptor complex |
| external side of plasma membrane |
| basolateral plasma membrane |
| GO Term |
|---|
| cytokine receptor activity |
| cytokine binding |
| protein-hormone receptor activity |
| peptide hormone binding |
| leptin receptor activity |
Sequence
MTCQKFYVVLLHWEFLYVITALNLAYPTSPWRFKLFCAPPSTTDDSFLSPAGVPNNTSSLKGASEALVEAKFNSTGIYVSELSKTIFHCCFGNEQGQNCSALTGNTEGKTLASVVKPLVFRQLGVNWDIECWMKGDLTLFICHMEPLLKNPFKNYDSKVHLLYDLPEVIDDLPLPPLKDSFQTVQCNCSVRECECHVPVPRAKVNYALLMYLEITSAGVSFQSPLMSLQPMLVVKPDPPLGLRMEVTDDGNLKISWDSQTKAPFPLQYQVKYLENSTIVREAAEIVSDTSLLVDSVLPGSSYEVQVRSKRLDGSGVWSDWSLPQLFTTQDVMYFPPKILTSVGSNASFCCIYKNENQTISSKQIVWWMNLAEKIPETQYNTVSDHISKVTFSNLKATRPRGKFTYDAVYCCNEQACHHRYAELYVIDVNINISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDNPSIRPTSELKNCVLQTDGFYECVFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVKAEITINTGLLKVSWEKPVFPENNLQFQIRYGLNGKEIQWKTHEVFDAKSKSASLPVSDLCAVYVVQVRCRRLDGLGYWSNWSSPAYTLVMDVKVPMRGPEFWRIMDGDITKKERNVTLLWKPLMKNDSLCSVRRYVVKHRTAHNGTWSQDVGNQTNLTFLWAESAHTVTVLAINSIGASLVNFNLTFSWPMSKVNAVQSLSAYPLSSSCVILSWTLSPNDYSLLYLVIEWKNLNDDDGMKWLRIPSNVNKYYIHDNFIPIEKYQFSLYPVFMEGVGKPKIINGFTKDDIAKQQNDAGLYVIVPIIISSCVLLLGTLLISHQRMKKLFWDDVPNPKNCSWAQGLNFQKPETFEHLFTKHAESVIFGPLLLEPEPVSEEISVDTAWKNKDEMVPAAMVSLLLTTPDSTRGSICISDQCNSANFSGAQSTQGTCEDECQSQPSVKYATLVSNVKTVETDEEQGAIHSSVSQCIARKHSPLRQSFSSNSWEIEAQAFFLLSDHPPNVISPQLSFSGLDELLELEGNFPEENHGEKSVYYLGVSSGNKRENDMLLTDEAGVLCPFPAHCLFSDIRILQESCSHFVENNLNLGTSGKNFVPYMPQFQSCSTHSHKIIENKMCDLTV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 55 | N-linked (GlcNAc...) asparagine |
|
||
| 56 | N-linked (GlcNAc...) asparagine |
|
||
| 73 | N-linked (GlcNAc...) asparagine |
|
||
| 98 | N-linked (GlcNAc...) asparagine |
|
||
| 187 | N-linked (GlcNAc...) asparagine |
|
||
| 275 | N-linked (GlcNAc...) asparagine |
|
||
| 345 | N-linked (GlcNAc...) asparagine |
|
||
| 356 | N-linked (GlcNAc...) asparagine |
|
||
| 431 | N-linked (GlcNAc...) asparagine |
|
||
| 514 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050855 | renal fibrosis | |
| DOID:10603 | glucose intolerance | |
| DOID:10763 | hypertension | |
| DOID:2018 | hyperinsulinism | |
| DOID:4195 | hyperglycemia | |
| DOID:4989 | pancreatitis | |
| DOID:576 | proteinuria | |
| DOID:6000 | congestive heart failure | |
| DOID:784 | chronic kidney disease | |
| DOID:9352 | type 2 diabetes mellitus |
