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MIRAGE
Pleckstrin homology domain-containing family G member 2

Summary
UniProt ID
Q6KAU7
Gene Symbol
  • Plekhg2
Gene ID
101497
Organism
Mus musculus (house mouse)
GlyGen
Q6KAU7
The O-GlcNAc Database
Q6KAU7
O-GlcNAcAtlas
Q6KAU7
Re-Glyco
Q6KAU7
Annotation
Keyword
  • Alternative splicing
  • Guanine-nucleotide releasing factor
  • Phosphoprotein
  • Reference proteome
  • Tumor suppressor
Gene Ontology (GO)
Displaying 1 entry
GO Term
regulation of actin filament polymerization
Displaying 1 entry
GO Term
guanyl-nucleotide exchange factor activity
Annotation information from UniProt.
Sequence
MPEGARGLSLPKPSLRLGCGHQGEVCDCAAVSDTPTAQAATTMASPRGSGSSTSLSTVGSEGDPSPACSASRPEPLPEPPIRLHLLPVGIQGSVKPSRLERVAREIVETERAYVRDLRSIVEDYLGPLMDGRALGLNMEQVGTLFANIEDIYEFSSELLEDLEGCSSAGGIAECFVQRSEDFDIYTLYCMNYPSSLALLRELSVSPPATLWLQERQAQLRHSLPLQSFLLKPVQRILKYHLLLQELGKHWAEGPDSGGREMVEEAIVSMTAVAWYINDMKRKQEHAARLQEVQRRLGGWTGPELSAFGELVLEGTFRGGGGGGPRLRGGERLLFLFSRMLLVAKRRGPEYTYKGHIFCCNLSVSETPRDPLGFKVSDLTIPKHRHLFQAKNQEEKRLWIHCLQRLFFENHPASIPAKAKQVLLENSLHCAPKSKHIPEPPTSPLDSPRPRDAPGFTPGRRNPAPSPRLSGSRRGRRQSEPAKEAYVIFPQNDKPQVKHAGSEGELHPSSELQPVSASGLPEDLEDAGPPTLDPSGTSITEEILELLNQRGLRDSGPATHDIPKFPRDSRVPVESEPLPFQSLPSRESSEEEEEEDLETDEREPSPLHVLEGLEGSSAAEIPCIPSLTDIPSEVPSLPEIPEAPCLPCLSDISGVFEVPCLSPTSTVPDIPSLATTPSFPCGSWLPGPLQEAAQPQATRRELLSGSNPGRLSESPSESREGQEDDTEGVSFSAVQREAGTSVQGFPEELEYRSCSEIRSAWQALEQGQLARPGFPEPLLILEDSDLRGGSTSGKTGMPHSERSASRVRELARLYSERIQQMQRAETRASTNAPRRRPRVLAQPQPSPCPPQEEAEPGALPAFGHVLVCELAFPLNCTQESVPLGPAVLVQAATPLCIQGDDLSGQNLNVSDLSKQGHLSSNSIPPPVPLPGQSNFQNIQVPSTSLLPKQEPPDVQVPTASTLPDTSQLQSQVPAATPSAGHRNCVEIQVQSTTSLPGQECQADTVALSKQEGHEDSQNPNKAPGAEQRDVSIDQGLAVVGGRPVSPLPVCTSSPDQQIPATTPLPLSTDFPDMEGPGALPLPTQEGRPDCSIPCNPLPSLSQDVQVPAVIPVSQLQGLTDTRATVPLSSHKQEDAPECLGPEPSLTDTPAPRLLSSLGQQNTTDGPVSAAAVPLTEQGCSQDLQGLITSPVQTTMELPKPRGLVSRVATSESLDLTPPHSPSLSTRQLLGPSAAALSRYLAASYISQSLARRQGPGGEGTVASQGHWSSSAPTSRAPSPPPQPQPPAPPARRLSYATTVSIQVGGGGRLRPAKAQVRLNHPALLAAPHPGAVGPSQGPGGS
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 3 entries
Position Description PubMed ID GlyTouCan ID Source
441
975
1208
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 4 entries
Pathway Name Organism
CDC42 GTPase cycle Mus musculus
G alpha (12/13) signalling events Mus musculus
NRAGE signals death through JNK Mus musculus
RAC1 GTPase cycle Mus musculus
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025