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Epigen

Summary

UniProt ID

Q6UW88

Gene Symbol

EPGN
UNQ3072/PRO9904

Gene ID

255324

Organism

Homo sapiens (human)

External Links

PubChem: Q6UW88
Re-Glyco: Q6UW88

Annotation

Keyword

3D-structure
Alternative splicing
Direct protein sequencing
Disulfide bond
EGF-like domain
Glycoprotein
Growth factor
Reference proteome
Secreted
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
clathrin-coated endocytic vesicle membrane
extracellular region
extracellular space
plasma membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 7** entries
GO Term
epidermal growth factor receptor signaling pathway
positive regulation of mitotic nuclear division
positive regulation of epithelial cell proliferation
MAPK cascade
positive regulation of MAPK cascade
angiogenesis
positive regulation of cell population proliferation

Displaying **all 3** entries
GO Term
epidermal growth factor receptor binding
transmembrane receptor protein tyrosine kinase activator activity
growth factor activity

Annotation information from UniProt.

Sequence

MALGVPISVYLLFNAMTALTEEAAVTVTPPITAQQGNWTVNKTEADNIEGPIALKFSHLCLEDHNSYCINGACAFHHELEKAICRCFTGYTGERCEHLTLTSYAVDSYEKYIAIGIGVGLLLSGFLVIFYCYIRKRCLKLKSPYNVCSGERRPL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
37	N-linked (GlcNAc...) asparagine			UniProt
41	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 15 in total

1

2

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Last »
Pathway Name	Organism
Cargo recognition for clathrin-mediated endocytosis	Homo sapiens
Clathrin-mediated endocytosis	Homo sapiens
Constitutive Signaling by Aberrant PI3K in Cancer	Homo sapiens
EGFR downregulation	Homo sapiens
EGFR interacts with phospholipase C-gamma	Homo sapiens
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	Homo sapiens
Extra-nuclear estrogen signaling	Homo sapiens
GAB1 signalosome	Homo sapiens
GRB2 events in EGFR signaling	Homo sapiens
Inhibition of Signaling by Overexpressed EGFR	Homo sapiens