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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
TIR domain-containing adapter molecule 1
Summary
- UniProt ID
- Q80UF7
- Gene Symbol
-
- Ticam1
- Trif
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Antiviral defense
- Apoptosis
- Cytoplasm
- Cytoplasmic vesicle
- Inflammatory response
- Innate immunity
- Isopeptide bond
- Mitochondrion
- Phosphoprotein
- Reference proteome
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| ripoptosome |
| autophagosome |
| mitochondrion |
| cytosol |
| endosome membrane |
| early endosome |
| GO Term |
|---|
| protein kinase binding |
| signaling adaptor activity |
Sequence
MDNPGPSLRGAFGILGALERDRLTHLKHKLGSLCSGSQESKLLHAMVLLALGQDTEARVSLESLKMNTVAQLVAHQWADMETTEGPEEPPDLSWTVARLYHLLAEENLCPASTRDMAYQVALRDFASQGDHQLGQLQNEAWDRCSSDIKGDPSGFQPLHSHQGSLQPPSASPAVTRSQPRPIDTPDWSWGHTLHSTNSTASLASHLEISQSPTLAFLSSHHGTHGPSKLCNTPLDTQEPQLVPEGCQEPEEISWPPSVETSVSLGLPHEISVPEVSPEEASPILPDALAAPDTSVHCPIECTELSTNSRSPLTSTTESVGKQWPITSQRSPQVPVGDDSLQNTTSSSPPAQPPSLQASPKLPPSPLSSASSPSSYPAPPTSTSPVLDHSETSDQKFYNFVVIHARADEQVALRIREKLETLGVPDGATFCEEFQVPGRGELHCLQDAIDHSGFTILLLTASFDCSLSLHQINHALMNSLTQSGRQDCVIPLLPLECSQAQLSPDTTRLLHSIVWLDEHSPIFARKVANTFKTQKLQAQRVRWKKAQEARTLKEQSIQLEAERQNVAAISAAYTAYVHSYRAWQAEMNKLGVAFGKNLSLGTPTPSWPGCPQPIPSHPQGGTPVFPYSPQPPSFPQPPCFPQPPSFPQPPSFPLPPVSSPQSQSFPSASSPAPQTPGPQPLIIHHAQMVQLGVNNHMWGHTGAQSSDDKTECSENPCMGPLTDQGEPLLETPE
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 175 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | Mus musculus |
| IKK complex recruitment mediated by RIP1 | Mus musculus |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | Mus musculus |
| Ligand-dependent caspase activation | Mus musculus |
| MyD88-independent TLR4 cascade | Mus musculus |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | Mus musculus |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | Mus musculus |
| TRIF-mediated programmed cell death | Mus musculus |
