TRAF6-mediated induction of TAK1 complex within TLR4 complex

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
UbK63polyUbTICAM1:TRAM:TLR4:LY96:LPS:CD14TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14Traf6K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complexTAK1 complexADPactivated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:activated TAK1 complexATPK63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025