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Sodium bicarbonate cotransporter 3
Summary
- UniProt ID
- Q8BTY2
- Gene Symbol
-
- Nbc3
- Slc4a7
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Cell projection
- Disulfide bond
- Glycoprotein
- Phosphoprotein
- Reference proteome
- Sodium transport
- Symport
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| basolateral plasma membrane |
| apical plasma membrane |
| stereocilium |
| cytoplasm |
| plasma membrane |
| GO Term |
|---|
| sodium:bicarbonate symporter activity |
| solute:inorganic anion antiporter activity |
| monoatomic anion transmembrane transporter activity |
Sequence
MEADGAGEQMRPLLTRGPDEEAVVDLGKTSSTVNTKFEKEELESHRAVYVGVHVPFSKESRRRHKHRGHKHHHRRRKDKDSDKEDGRESPSYDTPSQRVQFILGTEDDDEEHIPHDLFTEMDELCYRDGEEYEWKETARWLKFEEDVEDGGDRWSKPYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLDNMIASGQLDDSIRENVREALLKRHHHQNEKRFTSRIPLVRSFADIGILASPQSAPGNLDNSKSGEMKGNGSGGSRENSTVDFSKVDMNFMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLSGLTEVPVPTRFLFLLLGPAGKAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPKSVPSQEKRKIPVFPNGSAAMSVGPPKEDDHHAGPELQRTGRLFGGLILDIKRKAPFFLSDFKDALSLQCLASILFLYCACMSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCRDYHLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFHLGEIYAFNMHNNLDELTSYTCVCAEPSNPSNETLELWKRKNITAYSVSWGNLTVSECKTFHGMFVGSACGPHGPYVPDVLFWCVVLFFTTFFLSSFLKQFKTKGYFPTKVRSTISDFAVFLTIVIMVAIDYLVGIPSPKLHVPEKFEPTDPSRGWIISPLGDNPWWTLLIAAVPALLCTILIFMDQQITAVIINRKEHKLKFIPMPVLYGVFLYMGVSSLKGIQFFDRIKLFGMPAKHQPDLIYLRYVPLWKVHVFTVVQLTCLVLLWVIKASAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPESKKKKEDDKKKKEKEEAERMLQDDEDTVHLPFERGSLLQIPVKTLKYSIDPSVVNISDEMAKTAQWKALSMNTENAKVTRPNTSPEKPVSVTINFEDEPSKKYMDAETSL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 176 | N-linked (GlcNAc...) asparagine |
|
||
| 274 | N-linked (GlcNAc...) asparagine | |||
| 422 |
|
|||
| 644 | N-linked (GlcNAc...) asparagine |
|
||
| 654 | N-linked (GlcNAc...) asparagine |
|
||
| 664 | N-linked (GlcNAc...) asparagine |
|
G50282JC
G46503DX
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Bicarbonate transporters | Mus musculus |
| RHOD GTPase cycle | Mus musculus |
| RHOF GTPase cycle | Mus musculus |
| RHOH GTPase cycle | Mus musculus |
| RHOQ GTPase cycle | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110839 | Usher syndrome type 2C |
