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Beta-arrestin-1

Summary

UniProt ID

Q8BWG8

Gene Symbol

Arrb1

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q8BWG8
PubChem: Q8BWG8
The O-GlcNAc Database: Q8BWG8

Annotation

Keyword

Alternative splicing
Cell membrane
Cell projection
Coated pit
Cytoplasm
Cytoplasmic vesicle
Nucleus
Phosphoprotein
Protein transport
Reference proteome
Signal transduction inhibitor
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

Displaying entries **21 - 28** of 28 in total

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GO Term
follicle-stimulating hormone signaling pathway
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
ubiquitin-dependent protein catabolic process
phototransduction
positive regulation of MAPK cascade
positive regulation of peptidyl-serine phosphorylation
negative regulation of ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade

Displaying **all 10** entries
GO Term
nucleus
plasma membrane
cytoplasmic vesicle
postsynaptic membrane
pseudopodium
basolateral plasma membrane
cytosol
endosome
clathrin-coated pit
dendritic spine

Displaying entries **1 - 10** of 17 in total

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GO Term
G protein-coupled receptor binding
signaling receptor binding
enzyme binding
arrestin family protein binding
clathrin binding
nuclear estrogen receptor binding
mitogen-activated protein kinase kinase binding
alpha-1A adrenergic receptor binding
alpha-1B adrenergic receptor binding
follicle-stimulating hormone receptor binding

Annotation information from UniProt.

Sequence

MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHACPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDNVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEPPHREVPESETPVDTNLIELDTNDDDIVFEDFARQRLKGMKDDKDEEDDGTGSPHLNNR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
98			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 9** entries
Pathway Name	Organism
Activation of SMO	Mus musculus
Cargo recognition for clathrin-mediated endocytosis	Mus musculus
Clathrin-mediated endocytosis	Mus musculus
G alpha (s) signalling events	Mus musculus
Golgi Associated Vesicle Biogenesis	Mus musculus
Lysosome Vesicle Biogenesis	Mus musculus
MAP2K and MAPK activation	Mus musculus
Thrombin signalling through proteinase activated receptors (PARs)	Mus musculus
Ub-specific processing proteases	Mus musculus