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Wolframin
Summary
- UniProt ID
- Q8IMZ9
- Gene Symbol
-
- CG4917
- wfs1
- Gene ID
- 42679
- Organism
- Drosophila melanogaster (fruit fly)
Annotation
- Keyword
-
- Alternative splicing
- Endoplasmic reticulum
- Glycoprotein
- Mitochondrion
- Reference proteome
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| mitochondrion |
| endoplasmic reticulum membrane |
| GO Term |
|---|
| calcium ion homeostasis |
| adult locomotory behavior |
| endoplasmic reticulum unfolded protein response |
| negative regulation of gene expression |
| GO Term |
|---|
| ubiquitin protein ligase binding |
Sequence
MATWTQNEPTGVTKRRRWNLEDRASLNKLKHHIAEEGCPQMQYDLAKELLDNSIVEPNLAKGNQSQKAVNWLVSAAHNGHEDAVKLLRQCYNDGSGITAENTDEVRRCLAMTPGERAARKAARELFACLSNGNEHITPKQLERKMRRIYNLQRKRRRRDDDRSSSSSEGEQEPECEPLEDVPTIDLANVERRRLITEAHLVSAASNYSAGQMPSVNDALTLSVPDPRSLDHVPCFYRMIFHPLIFFTLFYHRLLNLIVSIPNVIPLSVRCSVLVAISWWSSRHMLPLVSYYLSLGIMIWATCKMLKTKQQFVDFRIWSGLFLSYGDQNIEADIAEHRFLRNNMKPYLYFFCAFICNLIVYPLVTDAWLPHSELTIISGALTFITMCVSMYASSHQLPDWLVIVSFAVNVLAKYPYEMDEVVSTRWRFLDLRVPTFSSFVIGNGIEFCLNCRTALYLFIPVLLIMMAKRSRWHGVYTFLIPHCVTLSWLQVCIATSQSSTVFGVMRAALGLAGIVLFLPLFGIVALLVPVFVAIDSLGLASEQLRWGSTALACGLVVVLSCILALNRATQKYITMLQLITAITTACLLVLPYMTSSFKDTPRFNAMPRAGLHSLSETNTLPWDRFHALCAQPVHEQPNKIKAQLRCSLLNGMPVIWEGSVTKVEISRVSNFLEDTIANYLPVWLGRMLRCLHGENISQHFKCDPKLDAQCEEWRSVFKTFNAQSGSCTLQRWNRYEYELLVKVGTKRSGRLLGRSTTTDVILRAHHDFGNFTRLLSEGDVVLFYGILHNSRLLADNVQVKLKTIECVECRSRDLGTASIERVVAASPMDARLQDLMRGIKYLLNALLNPLITFK
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Post-translational protein phosphorylation | Drosophila melanogaster |
| Regulation of IGF Activity by IGFBP | Drosophila melanogaster |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110629 | Wolfram syndrome 1 |
