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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Transmembrane protease serine 6
Summary
- UniProt ID
- Q8IU80
- Gene Symbol
-
- TMPRSS6
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q8IU80
- PubChem
- Q8IU80
- The Human Metabolome Database
- HMDBP08697
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Disease variant
- Disulfide bond
- Glycoprotein
- Reference proteome
- Repeat
- Serine protease
- Signal-anchor
- Transmembrane helix
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| self proteolysis |
| GO Term |
|---|
| extracellular space |
| plasma membrane |
| GO Term |
|---|
| serine-type endopeptidase activity |
| metalloendopeptidase activity |
Sequence
MLLLFHSKRMPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSKRKARGYLRLVPLFVLLALLVLASAGVLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQKMLKELITSTRLGTYYNSSSVYSFGEGPLTCFFWFILQIPEHRRLMLSPEVVQALLVEELLSTVNSSAAVPYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYVGQGQVLRLKGPDHLASSCLWHLQGPKDLMLKLRLEWTLAECRDRLAMYDVAGPLEKRLITSVYGCSRQEPVVEVLASGAIMAVVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQGVLSTPYFPSYYSPQTHCSWHLTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPYAERIPVVATAGITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPACDGVKDCPNGLDERNCVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 136 | N-linked (GlcNAc...) asparagine |
|
||
| 184 | N-linked (GlcNAc...) asparagine |
|
||
| 216 | N-linked (GlcNAc...) asparagine |
|
||
| 338 | N-linked (GlcNAc...) asparagine |
|
||
| 433 | N-linked (GlcNAc...) asparagine |
|
||
| 453 | N-linked (GlcNAc...) asparagine |
|
||
| 518 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Collagen degradation | Homo sapiens |
| Degradation of the extracellular matrix | Homo sapiens |
