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MIRAGE
Rho guanine nucleotide exchange factor 6
Summary
- UniProt ID
- Q8K4I3
- Gene Symbol
-
- Arhgef6
- Gene ID
- 73341
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Cell projection
- Guanine-nucleotide releasing factor
- Phosphoprotein
- Reference proteome
- SH3 domain
- Gene Ontology (GO)
| GO Term |
|---|
| cell-cell junction |
| lamellipodium |
| GO Term |
|---|
| intracellular signal transduction |
| lamellipodium assembly |
| GO Term |
|---|
| guanyl-nucleotide exchange factor activity |
Sequence
MNPEERLVTWLISLGVLESPKKTVCDPEEFLKSSLKNGVVLCKLINRLLPGSVEKYCLEPQTEADCIDNINDFLKGCATLQVEVFEPDDLYSGANFSKVLNTLLAVNKATEDQLSERPCGRSSSLSAATSSQTNPQVAVPSTAPEQHSEEKAEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKPSERPLSPKAIKGFDTAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEFTCLLGNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLNLMPHFKSMYLAYCANHPSAVNVLTQHSDDLERFMENQGASSPGILILTTSLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIIAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGDDIKTLGNVIFMSQVVMQHGACEEKEERYFLLFSSVLIMLSASPRMSGFMYQGKIPIAGMVVNRLDEIEGSDCMFEITGSTVERIVVHCNNNQDFQEWMEQLNRLTKGPTSCGSLSKTSSSSCSTHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKASEEEYVIRKSTAALEEDAQILKVIEAYCTSASFQQGTRKDSVPQVLLPEEEKLIIEETRSNGQTIIEEKSLVDTVYALKDEVKELKQENKKMKQCLEEELKSRKDLEKLVRKLLKQTDECIRSESSSKTSILQ
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 550 |
|
|
||
| 558 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CDC42 GTPase cycle | Mus musculus |
| G alpha (12/13) signalling events | Mus musculus |
| G beta:gamma signalling through CDC42 | Mus musculus |
| NRAGE signals death through JNK | Mus musculus |
| RAC1 GTPase cycle | Mus musculus |
| RHOU GTPase cycle | Mus musculus |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | Mus musculus |
