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Leukocyte immunoglobulin-like receptor subfamily B member 4

Summary

UniProt ID

Q8NHJ6

Gene Symbol

LILRB4
ILT3
LIR5

Organism

Homo sapiens (human)

External Links

GlyGen: Q8NHJ6
The Human Metabolome Database: HMDBP07781

Annotation

Keyword

3D-structure
Adaptive immunity
Alternative splicing
Cell membrane
Disulfide bond
Immunoglobulin domain
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 33 in total

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GO Term
cytokine-mediated signaling pathway
negative regulation of type II interferon production
negative regulation of T cell proliferation
negative regulation of interleukin-1 beta production
negative regulation of interleukin-10 production
negative regulation of interleukin-2 production
negative regulation of interleukin-5 production
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
positive regulation of CD8-positive, alpha-beta T cell differentiation

Displaying **all 4** entries
GO Term
cytoplasmic side of plasma membrane
cell surface
plasma membrane
extracellular exosome

Displaying **all 6** entries
GO Term
protein phosphatase binding
transmembrane receptor protein tyrosine kinase inhibitor activity
signaling receptor inhibitor activity
apolipoprotein binding
inhibitory MHC class I receptor activity
fibronectin binding

Annotation information from UniProt.

Sequence

MIPTFTALLCLGLSLGPRTHMQAGPLPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKEESPAPWDRQNPLEPKNKARFSIPSMTEDYAGRYRCYYRSPVGWSQPSDPLELVMTGAYSKPTLSALPSPLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRSEHGAQQHQAEFPMSPVTSVHGGTYRCFSSHGFSHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAAGPEDQPLMPTGSVPHSGLRRHWEVLIGVLVVSILLLSLLLFLLLQHWRQGKHRTLAQRQADFQRPPGAAEPEPKDGGLQRRSSPAADVQGENFCAAVKNTQPEDGVEMDTRQSPHDEDPQAVTYAKVKHSRPRREMASPPSPLSGEFLDTKDRQAEEDRQMDTEAAASEAPQDVTYAQLHSFTLRQKATEPPPSQEGASPAEPSVYATLAIH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites