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MIRAGE
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
C3d complexed with antigenComplex of CD19, CD81, CD225 and CD21 with C3d-bound AntigenComplex of CD19, CD81, CD225 and CD21LAIR1LAIR1:Collagen type XVIICollagen type XVII fibrilPVRCD96:PVRCD96LILR-interacting MHC Class I moleculesMHC Class I interacting with LILRsLILR setSELLL-selectin interacting with known ligandsL-selectin ligandsKLRC1HLA-E interacting with KLRC1:KLRD1HLA-ECD94KLRG1E-cadherin bound to KLRG1CDH1CRTAMCRTAM bound to NECL2PVRL2CD226:PVRCD226CD226 bound to Nectin 2CD200CD200 bound to CD200RCD200R1MHC Class I molecules interacting with CD160MHC Class I interacting with CD160CD160Antigen-bound Ig G AntibodyAntigen-bound antibody bound to lymphoid Fc gamma receptorsLymphoid-expressed Fc-gamma receptorsCD40 trimerCD40:CD40L trimerCD40LG trimerKIR2DL1HLA-C group 2 interacting with KIR2DL1HLA-C Cw3 (group 1)KIR3DL1HLA Bw4 interacting with KIR3DL1HLA-Bw4KIR3DL2HLA-A3 interacting with KIR3DL2HLA-A3KIR2DL4HLA-G interacting with KIR2DL4HLA-GHLA-C Cw4 (group 2)HLA-C group 2 interacting with KIR2DS1KIR2DS1 complexed with DAP12HLA-C group 1 interacting with KIR2DS2KIR2DS2 complexed with DAP12KLRB1 dimerCLEC2D dimer:KLRB1 dimerCLEC2D dimerSialic acidSIGLEC:sialic acidSIGLECHemagglutininNCR1:FCRG1A:CD3Z dimer:HemagglutininNCR1:FCRG1A:CD3Z dimerB7H6NCR3LG1:NCR3:FCRG3A:CD3Z dimerNCR3:FCRG1A:CD3Z dimerpp65CMVPP65:NCR3:FCRG3A:CD3Z dimerKLRF1 dimerKLRF1 dimer:CLEC2B dimerCLEC2B dimerSLAMF6SLAMF6 dimerSLAMF6:SLAMF6:SAP,EAT2SAP,EAT2CS1CS1:CS1OSCAROSCAR:Collagen I,II,III/SP-DCollagen types I,II,III/SP-DCollagen types I,IIILAIR2:Collagen type I,IIILAIR2TREM, CD300TRIM, CD300:lipidsCERA,PE,PSCD1:B2M:microbial lipidCD1:B2M:microbial lipid:TCRT-cell receptor complexCD1:B2M:self-lipid:TCRCD1:B2M:self-lipidPILRAPIANP:PILRAPIANP,NPDC1,CLEC4G,COLEC12 trimerCD99PILRA,PILRB:CD99PILRA,PILRBAntigen peptide bound class I MHCTCR interacting with antigen-bearing MHC Class IT-cell receptor complex with CD8HLA-C group 1 interacting with KIR2DL2/3HLA-C group-I-interacting KIRsNKG2D complexed with DAP10Ligand interacting with NKG2DNKG2D ligandVLA-4integrin alpha4beta1:VCAM1VCAM1AN100226ITGA4:ITGB1:natalizumabMADCAM1-1Integrin alpha4beta7:MADCAM1Integrin alpha4beta7ICAM 1-5LFA-1:ICAM 1-5Integrin alphaLbeta2AMICA1CXADR bound to JAMLCXADR
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying entries 1 - 10 of 27 in total
GlyCosmos Lectin UniProt ID Lectin Name Pathway Viewer
GL_000082 P20273 B-cell receptor CD22 view
GL_000152 Q92478 C-type lectin domain family 2 member B view
GL_000153 Q9UHP7 C-type lectin domain family 2 member D view
GL_000187 Q6UXB4 C-type lectin domain family 4 member G view
GL_000611 Q12918 Killer cell lectin-like receptor subfamily B member 1 view
GL_000625 Q9NZS2 Killer cell lectin-like receptor subfamily F member 1 view
GL_000629 Q96E93 Killer cell lectin-like receptor subfamily G member 1 view
GL_000639 P14151 L-selectin view
GL_000782 P20138 Myeloid cell surface antigen CD33 view
GL_000802 Q13241 Natural killer cells antigen CD94 view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025