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Myeloid cell surface antigen CD33

Summary

Lectin Name Aliases

Siglec-3

Organism

Homo sapiens (human)

External Links

UniProt

P20138

UniLectin

P20138

CarboGrove

1225

Annotation

Keyword

3D-structure
Alternative splicing
Cell adhesion
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Lectin
Peroxisome
Phosphoprotein
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 12 in total

1

2

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GO Term
cell adhesion
signal transduction
cell-cell signaling
negative regulation of cell population proliferation
positive regulation of protein secretion
cell-cell adhesion
negative regulation of interleukin-8 production
Fc-gamma receptor signaling pathway
negative regulation of interleukin-1 beta production
negative regulation of tumor necrosis factor production

Displaying **all 8** entries
GO Term
specific granule membrane
tertiary granule membrane
nucleoplasm
Golgi apparatus
external side of plasma membrane
cell surface
peroxisome
plasma membrane

Displaying **all 5** entries
GO Term
protein tyrosine phosphatase activator activity
carbohydrate binding
signaling receptor activity
protein phosphatase binding
sialic acid binding

Annotation information from UniProt.

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Homo sapiens
Neutrophil degranulation	Homo sapiens

UniLectin

UniProt
P20138

CarboGrove

Lectin Name: Siglec-3
Common Name: Siglec-3

Automated Analysis report (Top 10 high affinity glycans)

Array Source

ASYMN

Protein Source

Investigator Provided

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G29055YG	3692.5	602.08
G04576KS	2974.17	215.06
G83513YI	2933.17	179.72
G06209KS	2526.67	307.34
G14047PA	1953.67	396.58
G95288UB	1699.67	310.16
G84467IZ	1285	124.72
G97947UQ	1240.6	117.56
G91365ZQ	1132.83	229.03
G90825UM	1002.17	207.45

CarboGrove View

CarboGrove is populated with the results from 35 types of glycan arrays, 13 glycan families, 5 experimental methods, and 19 laboratories or companies by processing and interpreting data from various types of glycan arrays.