GlyCosmos Portal

Submissions

Myeloid cell surface antigen CD33

Summary

Organism: Homo sapiens (human)

External Links

UniProt

P20138

UniLectin

P20138

CarboGrove

1225

Annotation

Keyword

3D-structure
Alternative splicing
Cell adhesion
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Lectin
Peroxisome
Phosphoprotein
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 13 in total

1

2

Next ›

Last »
GO Term
cell adhesion
signal transduction
cell-cell signaling
negative regulation of cell population proliferation
positive regulation of protein secretion
cell-cell adhesion
positive regulation of protein tyrosine phosphatase activity
negative regulation of interleukin-1 beta production
negative regulation of tumor necrosis factor production
negative regulation of monocyte activation

Displaying **all 8** entries
GO Term
nucleoplasm
Golgi apparatus
external side of plasma membrane
cell surface
plasma membrane
peroxisome
specific granule membrane
tertiary granule membrane

Displaying **all 4** entries
GO Term
carbohydrate binding
signaling receptor activity
protein phosphatase binding
sialic acid binding

Annotation information from UniProt.

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Homo sapiens
Neutrophil degranulation	Homo sapiens

CarboGrove

Lectin Name: Siglec-3
Common Name: Siglec-3

Automated Analysis report (Top 10 high affinity glycans)

Array Source

ASYMN

Protein Source

Investigator Provided

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G29055YG	3692.5	602.07958984375
G04576KS	2974.1669921875	215.058502197265625
G83513YI	2933.1669921875	179.722503662109375
G06209KS	2526.6669921875	307.34259033203125
G14047PA	1953.6669921875	396.5806884765625
G95288UB	1699.6669921875	310.160400390625
G84467IZ	1285.0	124.718902587890625
G97947UQ	1240.5999755859375	117.56020355224609375
G91365ZQ	1132.8330078125	229.0287017822265625
G90825UM	1002.1669921875	207.454498291015625

CarboGrove View

MCAW-DB (Glycan Recognition Profile)

MCAW-DB is a database whereby users can view the multiple alignment analysis results obtained from the MCAW tool, which can computationally find common glycan substructures among a group of glycan structures. The data in MCAW-DB are analysis results of glycan array experiments; those glycans having higher binding affinity to glycan binding proteins (GBPs) have been analyzed and can be viewed as “glycan recognition profiles”. Currently, this database provides published analysis results of glycan array data from the Consortium for Functional Glycomics (CFG).