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Sortilin-related receptor

Summary

UniProt ID

Q92673

Gene Symbol

SORL1
C11orf32

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0012449

GlyConnect

1766

GlyGen

Q92673

PubChem

Q92673

Annotation

Keyword

3D-structure
Alzheimer disease
Amyloidosis
Cell membrane
Cleavage on pair of basic residues
Cytoplasmic vesicle
Direct protein sequencing
Disease variant
Disulfide bond
EGF-like domain
Endocytosis
Endoplasmic reticulum
Endosome
Glycoprotein
Golgi apparatus
Neurodegeneration
Phosphoprotein
Receptor
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix
Transport

Gene Ontology (GO)

Displaying entries **1 - 10** of 30 in total

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GO Term
positive regulation of insulin receptor signaling pathway
positive regulation of protein localization to early endosome
positive regulation of adipose tissue development
positive regulation of protein catabolic process
neuropeptide signaling pathway
positive regulation of endocytic recycling
post-Golgi vesicle-mediated transport
cell migration
negative regulation of neurogenesis
protein maturation

Displaying entries **1 - 10** of 23 in total

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GO Term
Golgi membrane
endosome
early endosome
endoplasmic reticulum
endoplasmic reticulum membrane
Golgi apparatus
trans-Golgi network
cell surface
Golgi cisterna
extracellular space

Displaying **all 7** entries
GO Term
transmembrane signaling receptor activity
amyloid-beta binding
low-density lipoprotein particle receptor activity
aspartic-type endopeptidase inhibitor activity
low-density lipoprotein particle binding
neuropeptide binding
small GTPase binding

Annotation information from UniProt.

Sequence

MATRSSRRESRLPFLFTLVALLPPGALCEVWTQRLHGGSAPLPQDRGFLVVQGDPRELRLWARGDARGASRADEKPLRRKRSAALQPEPIKVYGQVSLNDSHNQMVVHWAGEKSNVIVALARDSLALARPKSSDVYVSYDYGKSFKKISDKLNFGLGNRSEAVIAQFYHSPADNKRYIFADAYAQYLWITFDFCNTLQGFSIPFRAADLLLHSKASNLLLGFDRSHPNKQLWKSDDFGQTWIMIQEHVKSFSWGIDPYDKPNTIYIERHEPSGYSTVFRSTDFFQSRENQEVILEEVRDFQLRDKYMFATKVVHLLGSEQQSSVQLWVSFGRKPMRAAQFVTRHPINEYYIADASEDQVFVCVSHSNNRTNLYISEAEGLKFSLSLENVLYYSPGGAGSDTLVRYFANEPFADFHRVEGLQGVYIATLINGSMNEENMRSVITFDKGGTWEFLQAPAFTGYGEKINCELSQGCSLHLAQRLSQLLNLQLRRMPILSKESAPGLIIATGSVGKNLASKTNVYISSSAGARWREALPGPHYYTWGDHGGIITAIAQGMETNELKYSTNEGETWKTFIFSEKPVFVYGLLTEPGEKSTVFTIFGSNKENVHSWLILQVNATDALGVPCTENDYKLWSPSDERGNECLLGHKTVFKRRTPHATCFNGEDFDRPVVVSNCSCTREDYECDFGFKMSEDLSLEVCVPDPEFSGKSYSPPVPCPVGSTYRRTRGYRKISGDTCSGGDVEARLEGELVPCPLAEENEFILYAVRKSIYRYDLASGATEQLPLTGLRAAVALDFDYEHNCLYWSDLALDVIQRLCLNGSTGQEVIINSGLETVEALAFEPLSQLLYWVDAGFKKIEVANPDGDFRLTIVNSSVLDRPRALVLVPQEGVMFWTDWGDLKPGIYRSNMDGSAAYHLVSEDVKWPNGISVDDQWIYWTDAYLECIERITFSGQQRSVILDNLPHPYAIAVFKNEIYWDDWSQLSIFRASKYSGSQMEILANQLTGLMDMKIFYKGKNTGSNACVPRPCSLLCLPKANNSRSCRCPEDVSSSVLPSGDLMCDCPQGYQLKNNTCVKQENTCLRNQYRCSNGNCINSIWWCDFDNDCGDMSDERNCPTTICDLDTQFRCQESGTCIPLSYKCDLEDDCGDNSDESHCEMHQCRSDEYNCSSGMCIRSSWVCDGDNDCRDWSDEANCTAIYHTCEASNFQCRNGHCIPQRWACDGDTDCQDGSDEDPVNCEKKCNGFRCPNGTCIPSSKHCDGLRDCSDGSDEQHCEPLCTHFMDFVCKNRQQCLFHSMVCDGIIQCRDGSDEDAAFAGCSQDPEFHKVCDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFRCENGHCIPNRWKCDRENDCGDWSDEKDCGDSHILPFSTPGPSTCLPNYYRCSSGTCVMDTWVCDGYRDCADGSDEEACPLLANVTAASTPTQLGRCDRFEFECHQPKTCIPNWKRCDGHQDCQDGRDEANCPTHSTLTCMSREFQCEDGEACIVLSERCDGFLDCSDESDEKACSDELTVYKVQNLQWTADFSGDVTLTWMRPKKMPSASCVYNVYYRVVGESIWKTLETHSNKTNTVLKVLKPDTTYQVKVQVQCLSKAHNTNDFVTLRTPEGLPDAPRNLQLSLPREAEGVIVGHWAPPIHTHGLIREYIVEYSRSGSKMWASQRAASNFTEIKNLLVNTLYTVRVAAVTSRGIGNWSDSKSITTIKGKVIPPPDIHIDSYGENYLSFTLTMESDIKVNGYVVNLFWAFDTHKQERRTLNFRGSILSHKVGNLTAHTSYEISAWAKTDLGDSPLAFEHVMTRGVRPPAPSLKAKAINQTAVECTWTGPRNVVYGIFYATSFLDLYRNPKSLTTSLHNKTVIVSKDEQYLFLVRVVVPYQGPSSDYVVVKMIPDSRLPPRHLHVVHTGKTSVVIKWESPYDSPDQDLLYAVAVKDLIRKTDRSYKVKSRNSTVEYTLNKLEPGGKYHIIVQLGNMSKDSSIKITTVSLSAPDALKIITENDHVLLFWKSLALKEKHFNESRGYEIHMFDSAMNITAYLGNTTDNFFKISNLKMGHNYTFTVQARCLFGNQICGEPAILLYDELGSGADASATQAARSTDVAAVVVPILFLILLSLGVGFAILYTKHRRLQSSFTAFANSHYSSRLGSAIFSSGDDLGEDDEDAPMITGFSDDVPMVIA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 48 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
99	N-linked (GlcNAc...) asparagine	19159218	G06247RL G43669FQ G45395BF G20706XG G27058EU G41071NU G42124LM G62765YT	UniProt GlyGen
103				GlyGen
158	N-linked (GlcNAc...) asparagine		G79666IR G34989PA G45395BF G43223CG G37412TK G83229XP G08918WF G00912UN G61256FT G76295SF G27058EU G80920RR G64409MC G62765YT G31852PQ	UniProt GlyGen GlyConnect
367				GlyGen
368	N-linked (GlcNAc...) asparagine		G58954YZ G37412TK	UniProt GlyGen
430	N-linked (GlcNAc...) asparagine			UniProt GlyGen
616	N-linked (GlcNAc...) asparagine		G59626AS G72790NZ G10486CT G95865ZB G49955PK G11314AS G02815KT	UniProt GlyGen
674	N-linked (GlcNAc...) asparagine		G80920RR	UniProt GlyGen
758				GlyGen
818	N-linked (GlcNAc...) asparagine			UniProt GlyGen