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MIRAGE
Ubiquitin carboxyl-terminal hydrolase 7
Summary
- UniProt ID
- Q93009
- Gene Symbol
-
- HAUSP
- USP7
- Gene ID
- 7874
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Autism spectrum disorder
- Biological rhythms
- Chromosome
- Cytoplasm
- DNA repair
- Developmental protein
- Direct protein sequencing
- Disease variant
- Epilepsy
- Host-virus interaction
- Intellectual disability
- Isopeptide bond
- Nucleus
- Phosphoprotein
- Reference proteome
- Thiol protease
- Ubl conjugation
- Ubl conjugation pathway
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| chromosome |
| protein-containing complex |
| nucleoplasm |
| cytosol |
| PML body |
| nuclear body |
| GO Term |
|---|
| p53 binding |
| cysteine-type endopeptidase activity |
| cysteine-type deubiquitinase activity |
| deubiquitinase activity |
| K48-linked deubiquitinase activity |
Sequence
MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 74 |
|
|||
| 630 |
|
|||
| 802 |
|
G49108TO
G62765YT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Dual incision in TC-NER | Homo sapiens |
| Formation of TC-NER Pre-Incision Complex | Homo sapiens |
| Gap-filling DNA repair synthesis and ligation in TC-NER | Homo sapiens |
| Regulation of PTEN localization | Homo sapiens |
| Regulation of TP53 Degradation | Homo sapiens |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | Homo sapiens |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | Homo sapiens |
| Ub-specific processing proteases | Homo sapiens |
