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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Sialic acid-binding Ig-like lectin 12
Summary
- UniProt ID
- Q96PQ1
- Gene Symbol
-
- SIGLEC12
- SIGLECL1
- SLG
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q96PQ1
- The Human Metabolome Database
- HMDBP14239
- The O-GlcNAc Database
- Q96PQ1
Annotation
- Keyword
-
- Alternative splicing
- Cell adhesion
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Lectin
- Phosphoprotein
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| cell adhesion |
| GO Term |
|---|
| plasma membrane |
| GO Term |
|---|
| carbohydrate binding |
| sialic acid binding |
Sequence
MLLLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSPEEGEIQYASLSFHKARPQYPQEQEAIGYEYSEINIPK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 140 | N-linked (GlcNAc...) asparagine |
|
||
| 179 | N-linked (GlcNAc...) asparagine |
|
||
| 230 | N-linked (GlcNAc...) asparagine |
|
||
| 269 |
|
|||
| 272 |
|
|||
| 276 |
|
|||
| 282 |
|
|||
| 290 | N-linked (GlcNAc...) asparagine |
|
||
| 360 | N-linked (GlcNAc...) asparagine |
|
||
| 367 | N-linked (GlcNAc...) asparagine |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0014667 | disease of metabolism | |
| DOID:10283 | prostate cancer | |
| DOID:10286 | prostate carcinoma | |
| DOID:305 | carcinoma | |
| DOID:4015 | sarcomatoid carcinoma | |
| DOID:640 | encephalomyelitis | |
| DOID:8544 | chronic fatigue syndrome | |
| DOID:9074 | systemic lupus erythematosus | |
| DOID:9970 | obesity |
