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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Proheparin-binding EGF-like growth factor
Summary
- UniProt ID
- Q99075
- Gene Symbol
-
- HBEGF
- DTR
- DTS
- HEGFL
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- Q99075
- PubChem
- Q99075
- The Human Metabolome Database
- HMDBP02701
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Growth factor
- Heparin-binding
- Receptor
- Reference proteome
- Secreted
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| cell surface |
| extracellular region |
| extracellular space |
| plasma membrane |
| endocytic vesicle membrane |
| clathrin-coated endocytic vesicle membrane |
Sequence
MKLLPSVVLKLFLAAVLSALVTGESLERLRRGLAAGTSNPDPPTVSTDQLLPLGGGRDRKVRDLQEADLDLLRVTLSSKPQALATPNKEEHGKRKKKGKGLGKKRDPCLRKYKDFCIHGECKYVKELRAPSCICHPGYHGERCHGLSLPVENRLYTYDHTTILAVVAVVLSSVCLLVIVGLLMFRYHRRGGYDVENEEKVKLGMTNSH
Glycosylation Sites
G57321FI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cargo recognition for clathrin-mediated endocytosis | Homo sapiens |
| Clathrin-mediated endocytosis | Homo sapiens |
| Constitutive Signaling by Aberrant PI3K in Cancer | Homo sapiens |
| Downregulation of ERBB2 signaling | Homo sapiens |
| EGFR Transactivation by Gastrin | Homo sapiens |
| EGFR downregulation | Homo sapiens |
| EGFR interacts with phospholipase C-gamma | Homo sapiens |
| ERBB2 Activates PTK6 Signaling | Homo sapiens |
| ERBB2 Regulates Cell Motility | Homo sapiens |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | Homo sapiens |
