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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Toll-like receptor 2 type-1
Summary
- UniProt ID
- Q9DD78
- Gene Symbol
-
- TLR2-1
- Organism
- Gallus gallus (chicken)
External Links
- PubChem
- Q9DD78
Annotation
- Keyword
-
- Disulfide bond
- Glycoprotein
- Inflammatory response
- Innate immunity
- Leucine-rich repeat
- NAD
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| inflammatory response |
| innate immune response |
| toll-like receptor signaling pathway |
| GO Term |
|---|
| plasma membrane |
| GO Term |
|---|
| transmembrane signaling receptor activity |
| signaling receptor activity |
| NAD+ nucleotidase, cyclic ADP-ribose generating |
| triacyl lipopeptide binding |
Sequence
MFNQSKQKPTMKLMWQAWLIYTALAAHLPEEQALRQACLSCDATQSCNCSFMGLDFIPPGLTGKITVLNLAHNRIKLIRTHDLQKAVNLRTLLLQSNQISSIDEDSFGSQGKLELLDLSNNSLAHLSPVWFGPLFSLQHLRIQGNSYSDLGESSPFSSLRNLSSLHLGNPQFSIIRQGNFEGIVFLNTLRIDGDNLSQYEPGSLKSIRKINHMIISIRRIDVFSAVIRDLLHSAIWLEVREIKLDIENEKLVQNSTLPLTIQKLTFTGASFTDKYISQIAVLLKEIRSLRELEAIDCVLEGKGAWDMTEIARSKQSSIETLSITNMTILDFYLFFDLEGIETQVGKLKRLSIASSKVFMVPCRLARYFSSLLYLDFHDNLLVNNRLGETICEDAWPSLQTLNLSKNSLKSLKQAARYISNLHKLINLDISENNFGEIPDMCEWPENLKYLNLSSTQIPKLTTCIPSTLEVLDVSANNLQDFGLQLPFLKELYLTKNHLKTLPEATDIPNLVAMSISRNKLNSFSKEEFESFKQMELLDASANNFICSCEFLSFIHHEAGIAQVLVGWPESYICDSPLTVRGAQVGSVQLSLMECHRSLLVSLICTLVFLFILILVVVGYKYHAVWYMRMTWAWLQAKRKPKRAPTKDICYDAFVSYSENDSNWVENIMVQQLEQACPPFRLCLHKRDFVPGKWIVDNIIDSIEKSHKTLFVLSEHFVQSEWCKYELDFSHFRLFDENNDVAILILLEPIQSQAIPKRFCKLRKIMNTKTYLEWPPDEEQQQMFWENLKAALKS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 48 | N-linked (GlcNAc...) asparagine |
|
||
| 120 | N-linked (GlcNAc...) asparagine |
|
||
| 161 | N-linked (GlcNAc...) asparagine |
|
||
| 195 | N-linked (GlcNAc...) asparagine |
|
||
| 254 | N-linked (GlcNAc...) asparagine |
|
||
| 325 | N-linked (GlcNAc...) asparagine |
|
||
| 402 | N-linked (GlcNAc...) asparagine |
|
||
| 451 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| MyD88:TIRAP-dependent cascade initiated on plasma membrane | Gallus gallus |
| NFkB and MAPK activation mediated by TRAF6 | Gallus gallus |
| TLR2 subfamily cascade | Gallus gallus |
