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MIRAGE
NFkB and MAPK activation mediated by TRAF6

Summary
Species
Gallus gallus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
TRAF6chTRAF6 bound to the activated chicken TLR complexp-IRAK2 bound to the activated chicken TLR complexTRAF6:p-IRAK2ch p-IRAK4 bound to the activated TLR complexoligo TRAF6 : p-IRAK2pUb oligo TRAF6 : p-IRAK2Ubiquitinfree K63_polyubiquitin chainp-IRAK2:pUb oligo TRAF6 : TAK1 :TAB1 : TAB2/TAB3 : free K63 pUb chainsTAK1 : TAB1 : TAB2/TAB3 complexATPADPp-IRAK2: pUb_oligo TRAF6 : phospho TAK1 :TAB1 : TAB2/TAB3 : K63linked free pUb chain
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying 1 entry
UniProt ID Protein Name Gene Symbol Pathway Viewer
Q9DD78 Toll-like receptor 2 type-1
  • TLR2-1
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: February 17, 2025