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Summary
- UniProt ID
- Q9EP53
- Gene Symbol
-
- Kiaa0243
- Tsc1
- Gene ID
- 64930
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Chaperone
- Coiled coil
- Cytoplasm
- Isopeptide bond
- Lysosome
- Membrane
- Phosphoprotein
- Reference proteome
- Tumor suppressor
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| cytoplasm |
| actin filament |
| cell cortex |
| cytosol |
| perinuclear region of cytoplasm |
| lysosomal membrane |
| lipid droplet |
| postsynaptic density |
| lamellipodium |
| GO Term |
|---|
| Hsp70 protein binding |
| ATPase inhibitor activity |
| protein folding chaperone |
| Hsp90 protein binding |
Sequence
MAQLANIGELLSMLDSSTLGVRDDVTAIFKESLNSERGPMLVNTLVDYYLETNSQPVLHILTTLQEPHDKHLLDKINEYVGKAATRLSILSLLGHVVRLQPSWKHKLSQAPLLPSLLKCLKMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVTEVYLVHLHASVYALFHRLYGMYPCNFVSFLRSHYSMKENVETFEEVVKPMMEHVRIHPELVTGSKDHELDPRRWKTLETHDVVIECAKISLDPTEASYEDGYSVSHQLSACFPYRSADVTTSPYVDTQNSYGGSTSTPSSSSRLMLFSPPGQLPQSLSSPSTRLLPEPLQASLWSPSAVCGMTTPPTSPGNVPADLSHPYSKAFGTTAGGKGTPSGTPATSPPPAPPCPQDDCVHGSAAQASATAPRKEERADSSRPYLHRQSNDRGLEDPPGSKGSVTLRNLPDFLGDLASEEDSIEKDKEEAAISKELSEITTAEADPVVPRGGFDSPFYRDSLSGSQRKTHSAASGTQGSSVNPEPLHSSLDKHGPDTPKQAFTPIDPPSGSADVSPAGDRDRQTSLETSILTPSPCKIPPQRGVSFGSGQLPPYDHLFEVALPKTACHFVSKKTEELLKKVKGNPEEDCVPSTSPMEVLDRLIEQGAGAHSKELSRLSLPSKSVDWTHFGGSPPSDELRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIRAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYSQLQEQRDTMVTQLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRVELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQSKHPDTTKEVEMMKTAYRKELEKNRSHLLQQNQRLDASQRRVLELESLLAKKDHLLLEQKKYLEDVKSQASGQLLAAESRYEAQRKITRVLELEILDLYGRLEKDGRLRKLEEDRAEAAEAAEERLDCCSDGCTDSLVGHNEEASGHNGETRTSRPGGTRASCGGRVTGGSSSSSSELSTPEKPPSQRFSSRWEPALGEPSSSIPTTVGSLPSSKSFLGMKARELFRNKSESQCDEDSVTMSSSSLSETLKTELGKDSGTENKTSLSLDAPHPSSPNSDNVGQLHIMDYNETHPEHS
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Energy dependent regulation of mTOR by LKB1-AMPK | Mus musculus |
| Inhibition of TSC complex formation by PKB | Mus musculus |
| Macroautophagy | Mus musculus |
| TBC/RABGAPs | Mus musculus |
| TP53 Regulates Metabolic Genes | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060041 | autism spectrum disorder | |
| DOID:0060564 | spinal disease | |
| DOID:0060648 | anterior segment dysgenesis | |
| DOID:0110861 | autosomal recessive polycystic kidney disease | |
| DOID:13515 | tuberous sclerosis |
